254762-25-9Relevant academic research and scientific papers
Synthesis of deuterium labelled 4'-hydroxydiclofenac
Waterhouse, Ian
, p. 1075 - 1083 (2007/10/03)
Diclofenac is a potentially useful substrate for the study of drug-drug interactions caused by modulation of the activity of specific isoforms of cytochrome P450. The synthesis of a deuterium labelled version of its principal human metabolite, 4'-hydroxydiclofenac, for use as an internal standard in LC-MS-MS studies, is described.
