908129-34-0

Basic information

• Product Name: (S)-2-(1,3-dioxoisoindolin-2-yl)-3-phenyl-N-(quinolin-8-yl)propanamide
• Synonyms: (S)-2-(1,3-dioxoisoindolin-2-yl)-3-phenyl-N-(quinolin-8-yl)propanamide
• CAS NO: 908129-34-0
• Molecular Weight: 421.455
• Mol File: 908129-34-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: (S)-2-(1,3-dioxoisoindolin-2-yl)-3-phenyl-N-(quinolin-8-yl)propanamide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(1,3-dioxoisoindolin-2-yl)-3-phenyl-N-(quinolin-8-yl)propanamide(908129-34-0)
• EPA Substance Registry System: (S)-2-(1,3-dioxoisoindolin-2-yl)-3-phenyl-N-(quinolin-8-yl)propanamide(908129-34-0)

Safety Data

• Hazardous Substances Data: 908129-34-0(Hazardous Substances Data)

Upstream product

• 908129-33-9 (S)-2-(1,3-dioxoisoindolin-2-yl)-N-(quinolin-8-yl)propanamide 
• 591-50-4 iodobenzene 
• 14148-42-6 8-hydrazinoquinoline 
• 5123-55-7 Nα-phthaloyl-L-phenylalanine 
• 85-44-9 phthalic anhydride 
• 63-91-2 L-phenylalanine 
• 4306-25-6 (S)-2-phthalimidopropionyl chloride 
• 22509-74-6 N-ethoxycarbonylphthalimide 
• 4192-28-3 Phth-L-Ala-OH 
• 578-66-5 8-amino quinoline 
• 32150-91-7 phthaloyl-L-phenylalanyl chloride 

Downstream Products

• 1380433-20-4 2S,3S-N-(2-phthalimido-3-phenyl-3-(thiophene-2-yl)propionyl)-8-aminoquinoline 
• 1380433-27-1 C₂₆H₁₈⁽²⁾HN₃O₃ 
• 1449299-57-3 C₂₉H₂₃N₃O₅ 
• 1449299-58-4 C₂₉H₂₃N₃O₅ 
• 1449299-94-8 C₁₉H₁₇N₅O 
• 1449299-96-0 C₂₄H₂₅N₅O₃ 
• 128677-95-2 (2S,3S)-2-azido-3-phenylbutanoic acid 
• 25488-25-9 (2S,3S)-methylphenylalanine 
• 90731-57-0 (βS)-N-(tert-butoxycarbonyl)-β-methyl-L-phenylalanine 
• 1471990-94-9 C₃₀H₂₅N₃O₅ 
• 1471990-95-0 C₃₂H₂₉N₃O₅ 
• 1471990-96-1 C₃₅H₂₇N₃O₅ 

Relevant articles and documents

Palladium-catalyzed trifluoroacetate-promoted mono-arylation of the β-methyl group of alanine at room temperature: Synthesis of β-arylated α-amino acids through sequential C-H functionalization

We report a highly efficient and practical protocol for palladium-catalyzed N-quinolylcarboxamide (AQ)-directed arylation of the unactivated β-C(sp3)-H bonds of alanine with aryl iodides at room temperature. For the first time, a broad range of easily accessible aryl iodides can be installed onto the β-methyl group of AQ-coupled phthaloyl alanine mono-selectively, providing both natural and unnatural aromatic α-amino acids. Access to these mono-arylated compounds enables subsequent AQ-directed diastereoselective C-H functionalization, allowing the preparation of various β-disubstituted aromatic α-amino acids in a programmable manner.

Sulfonamide-promoted palladium(II)-catalyzed alkylation of unactivated methylene C(sp3)-H bonds with alkyl iodides

The alkylation of unactivated b-methylene C(sp3)-H bonds of a-amino acid substrates with a broad range of alkyl iodides using Pd(OAc)2 as the catalyst is described. The addition of NaOCN and 4-Cl-C6H4SO2/s

Divergent and Stereoselective Synthesis of β-Silyl-α-Amino Acids through Palladium-Catalyzed Intermolecular Silylation of Unactivated Primary and Secondary C?H Bonds

A general and practical PdII-catalyzed intermolecular silylation of primary and secondary C?H bonds of α-amino acids and simple aliphatic acids is reported. This method provides divergent and stereoselective access to a variety of optical pure