255043-87-9Relevant academic research and scientific papers
Substituent effects on the amination of racemic allyl carbonates using commercially available chiral rhodium catalysts
Atallah, Timothy,Blankespoor, Ronald L.,Homan, Philip,Hulderman, Chase,Samas, Brian M.,Van Allsburg, Kurt,Vrieze, Derek C.
, p. 5795 - 5798 (2013/10/01)
In the presence of commercially available chiral rhodium catalysts, a competitive benzy lamination of racemic allyl carbonates, substituted with p-X-Ph groups, shows that the reaction proceeds faster with substituents (X) that are more electron-withdrawing. Mechanistic implications of these results are discussed.
Readily Available [2.2.2]-Bicyclooctadienes as New Chiral Ligands for Ir(I): Catalytic, Kinetic Resolution of Allyl Carbonates
Fischer, Christian,Defieber, Christian,Suzuki, Takeyuki,Carreira, Erick M.
, p. 1628 - 1629 (2007/10/03)
We report an Ir(I)-catalyzed kinetic resolution of secondary allylic carbonates allowing for their isolation in up to 98% ee. Importantly, the study documents the synthesis and use of a new class of chiral [2.2.2]-bicyclooctadiene ligands for iridium. Cop
A stereospecific ruthenium-catalyzed allylic alkylation
Trost, Barry M.,Fraisse, Pierre L.,Ball, Zachary T.
, p. 1059 - 1061 (2007/10/03)
Good regioselectivity and chirality transfer for aryl-substituted allyl units is achieved in allylic alkylations with a wide range of nucleophiles by using the highly active ruthenium catalyst 1. This method provides a route to antidepressants such as (-)-fluoxetine from (S)-ephedrine (see scheme; Cp* = η5-C5Me5, TBAT = tetrabutylammonium triphenyldifluorosilicate).
