66583-43-5

Upstream product

• 321-98-2 (1S,2R)-(+)-ephedrine 
• 74-88-4 methyl iodide 
• 42151-56-4 (1S,2R)-(+)-N-methylephedrine 
• 4518-66-5 (1S,2S)-(-)-1-phenyl-1-propene oxide 
• 48115-38-4 norepinephrine 
• 90-81-3 ephedrine 
• 100-52-7 benzaldehyde 
• 119-51-7 1-phenyl-1,2-propanedione 2-oxime 
• 5265-18-9 (+/-)-cathinone 
• 26251-08-1 2-nitro-1-phenylpropan-1-ol 
• 63829-88-9 2-hydroxyamino-1-phenyl-propan-1-ol 

Downstream Products

• 104713-12-4 (R)-1-phenylprop-2-en-1-ol 
• 54163-70-1 (1S,2R)-N,N-dimethylephedrinium chloride 
• 444575-92-2 (R)-(-)-1-phenyl-1-(4-trifluoromethylphenoxy)-2-propene 
• 444575-93-3 (R)-(-)-1-phenyl-1-(2-methylphenoxy)-2-propene 
• 255043-87-9 (R)-(+)-1-phenyl-prop-2-enyl methyl carbonate 
• 180961-71-1 (R)-3-phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-ol 
• 180961-72-2 (R)-3-phenyl-2-(o-tolyloxy)propan-1-ol 
• 115290-79-4 (R)-3-(2-methylphenoxy)-3-phenylprop-1-yl methanesulfonate 
• 138110-76-6 (R)-3-(4-trifluoromethylphenoxy)-3-phenylprop-1-yl methanesulfonate 
• 54910-89-3 (R)-fluoxetine 
• 105314-52-1 (R)-tomoxetine 

Relevant academic research and scientific papers

NOVEL METHOD FOR PREPARATION OF AMMONIUM SALTS OF ESOMEPRAZOLE

The present invention relates to a process for the preparation of quartenary ammoniumsalts of esomeprazole. Further, the present invention also relates to the use quartenary ammoniumsalts of esomeprazole for the treatment of gastrointestinal disorders, pharmaceutical compositions containing them as well as the quartenary ammoniumsalts of esomeprazole, as such.

A stereospecific ruthenium-catalyzed allylic alkylation

Good regioselectivity and chirality transfer for aryl-substituted allyl units is achieved in allylic alkylations with a wide range of nucleophiles by using the highly active ruthenium catalyst 1. This method provides a route to antidepressants such as (-)-fluoxetine from (S)-ephedrine (see scheme; Cp* = η5-C5Me5, TBAT = tetrabutylammonium triphenyldifluorosilicate).