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METHYL 4-CHLORO-3,5-DINITROBENZOATE, with the molecular formula C8H6ClNO5, is a yellow, crystalline solid that is insoluble in water but soluble in organic solvents. It is a chemical compound often utilized as a precursor in the synthesis of other organic compounds.

2552-45-6

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2552-45-6 Usage

Uses

Used in Chemical Synthesis:
METHYL 4-CHLORO-3,5-DINITROBENZOATE is used as a precursor for the synthesis of other organic compounds, playing a crucial role in the creation of various chemical products.
Used in Dye Manufacturing:
In the dye industry, METHYL 4-CHLORO-3,5-DINITROBENZOATE is used as a key component in the manufacturing process, contributing to the development of different types of dyes.
Used in Pharmaceutical Production:
METHYL 4-CHLORO-3,5-DINITROBENZOATE is also utilized in the pharmaceutical sector, where it serves as a vital ingredient in the production of certain drugs.
Safety Note:
METHYL 4-CHLORO-3,5-DINITROBENZOATE is a hazardous chemical, and it is essential to handle it with care and in accordance with proper safety protocols to ensure the safety of individuals and the environment.

Check Digit Verification of cas no

The CAS Registry Mumber 2552-45-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,5 and 2 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2552-45:
(6*2)+(5*5)+(4*5)+(3*2)+(2*4)+(1*5)=76
76 % 10 = 6
So 2552-45-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H5ClN2O6/c1-17-8(12)4-2-5(10(13)14)7(9)6(3-4)11(15)16/h2-3H,1H3

2552-45-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name METHYL 4-CHLORO-3,5-DINITROBENZOATE

1.2 Other means of identification

Product number -
Other names Benzoic acid,4-chloro-3,5-dinitro-,methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2552-45-6 SDS

2552-45-6Relevant academic research and scientific papers

HIGHLY ACTIVE STING PROTEIN AGONIST COMPOUND

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Paragraph 0410-0412, (2021/07/17)

The present invention provides compounds of Formula (I) or (II), pharmaceutical compositions thereof, and methods of using compounds of Formula (I) or (II) to prevent and/or treat immune-related disorders.

ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF

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Page/Page column 9; 110; 111, (2018/04/11)

The present invention relates to heterocyclic compounds of Formula I useful as anti-infective agents. The present invention further relates to a method of treating an infection by administering such compounds, and to pharmaceutical compositions comprising such compounds.

DENDRITIC COMPOUNDS INCLUDING A CHELATING, FLUOROCHROME OR RECOGNITION AGENT, COMPOSITIONS INCLUDING SAME AND USES THEREOF

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Paragraph 0350; 0351; 0352, (2016/08/29)

The invention relates to dendritic compounds comprising a chelating, fluorochrome or recognition agent of formula (I), to compositions comprising same, and to uses thereof, wherein in said formula (I): T, L1, D, R, L2, V and n are as defined in the description.

Second generation of BACE-1 inhibitors part 2: Optimisation of the non-prime side substituent

Charrier, Nicolas,Clarke, Brian,Demont, Emmanuel,Dingwall, Colin,Dunsdon, Rachel,Hawkins, Julie,Hubbard, Julia,Hussain, Ishrut,Maile, Graham,Matico, Rosalie,Mosley, Julie,Naylor, Alan,O'Brien, Alistair,Redshaw, Sally,Rowland, Paul,Soleil, Virginie,Smith, Kathrine J.,Sweitzer, Sharon,Theobald, Pam,Vesey, David,Walter, Daryl S.,Wayne, Gareth

scheme or table, p. 3669 - 3673 (2010/03/24)

Our first generation of hydroxyethylamine transition-state mimetic BACE-1 inhibitors allowed us to validate BACE-1 as a key target for Alzheimer's disease by demonstrating amyloid lowering in an animal model, albeit at rather high doses. Finding a molecul

Discovery and optimization of antibacterial AccC inhibitors

Cheng, Cliff C.,Shipps Jr., Gerald W.,Yang, Zhiwei,Sun, Binyuan,Kawahata, Noriyuki,Soucy, Kyle A.,Soriano, Aileen,Orth, Peter,Xiao, Li,Mann, Paul,Black, Todd

scheme or table, p. 6507 - 6514 (2010/05/17)

The biotin carboxylase (AccC) is part of the multi-component bacterial acetyl coenzyme-A carboxylase (ACCase) and is essential for pathogen survival. We describe herein the affinity optimization of an initial hit to give 2-(2-chlorobenzylamino)-1-(cyclohe

Tricyclic benzimidazoles and their use as metabotropic glutamate receptor modulators

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Page/Page column 37-38, (2008/06/13)

The invention provides for a compound of formula (I) or a pharmaceutically acceptable salt thereof: wherein R1, R2, R3, A, B, D, m, n, x, and y are defined as described in the specification. The invention additionally provides a pharmaceutically composition comprising the compound of formula I, together with a method of using the same to treat or prevent neurological and psychiatric disorders. The compounds are useful in therapy related to the treatment or prevention of mGluR2 receptor-mediated disorders.

Synthesis and antibacterial activity of some substituted 3-(aryl)- and 3-(heteroaryl)indoles

Al-Hiari, Yusuf M.,Qaisi, Ali M.,El-Abadelah, Mustafa M.,Voelter, Wolfgang

, p. 243 - 248 (2007/10/03)

A synthesis of 3-(4-methoxycarbonyl-2,6-dinitrophenyl)indole, its 2,6-diamino analog, and 3-(2-amino-4-trifluoromethyl-6-nitrophenyl)indole is described. 4-(Trifluoromethyl)phenyl derivatives exhibit higher antibacterial potency than the former 4-(methoxy

Effects of ortho- and para-ring activation on the kinetics of S NAr reactions of 1-chloro-2-nitro- and 1-phenoxy-2-nitrobenzenes with aliphatic amines in acetonitrile

Crampton, Michael R.,Emokpae, Thomas A.,Isanbor, Chukwuemeka,Batsanov, Andrei S.,Howard, Judith A. K.,Mondal, Raju

, p. 1222 - 1230 (2007/10/03)

Rate constants are reported for reaction of 4-substituted 1-chloro-2,6-dinitrobenzenes 1, 6-substituted 1-chloro-2,4-dinitrobenzenes 2, and some of the corresponding 1-phenoxy derivatives, 3 and 4, with n-butylamine, pyrrolidine and pi-peridine in acetoni

HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE

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Page 25, (2010/02/07)

The present invention relates to novel hydroxyethylamine compounds of formula (I): (I) having Asp2 (-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated-amyloid levels or-amyloid deposits, particularly Alzheimer's disease.

Synthesis of Polyfunctionalized Biphenyls as Intermediates for a New Class of Liquid Crystals

Manka, Jason T.,Guo, Fengli,Huang, Jianping,Yin, Huiyong,Farrar, John M.,Sienkowska, Monika,Benin, Vladimir,Kaszynski, Piotr

, p. 9574 - 9588 (2007/10/03)

A series of hexa- and octasubstituted biphenyls containing halogen, amino, nitro, and propylthio substituents were prepared by metal-mediated convergent synthesis from halobenzene precursors. The Pd-assisted C-C coupling methods were ineffective in the fo

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