25530-11-4Relevant academic research and scientific papers
Mechanistic diversity in acetophenone transfer hydrogenation catalyzed by ruthenium iminophosphonamide complexes
Kalsin, Alexander M.,Peganova, Tatyana A.,Sinopalnikova, Iana S.,Fedyanin, Ivan V.,Belkova, Natalia V.,Deydier, Eric,Poli, Rinaldo
, p. 1473 - 1484 (2020)
A series of arene ruthenium iminophosphonamide complexes, [(Arene)RuCl{R2P(NR′)2}] (1), bearing various arenes and R,R′ substituents on the NPN ligand have been investigated as precatalysts in acetophenone transfer hydrogenation in b
Primary Amination of Ar2P(O)-H with (NH4)2CO3as an Ammonia Source under Simple and Mild Conditions and Its Extension to the Construction of Various P-N or P-O Bonds
Han, Ya-Ping,Tan, Yushi,Yang, Shang-Dong,Zhang, Hong-Yu,Zhang, Yuecheng,Zhao, Jiquan
, (2022/02/10)
A facile and efficient method for the synthesis of primary phosphinamides from Ar2P(O)-H reagents with stable and readily available ammonium carbonate as an ammonia source is disclosed herein for the first time. This ethyl bromoacetate-mediated primary am
A practical method for N-alkylation of phosphinic (thio)amides with alcohols via transfer hydrogenation
Jankins, Tanner C.,Qin, Zi-Yang,Engle, Keary M.
supporting information, p. 3272 - 3281 (2019/05/15)
This manuscript describes a modular method for preparing N-alkyl phosphinic amides from primary or secondary alcohols and primary phosphinic amide (R1R2P = ONH2) nucleophiles via transfer hydrogenation. The transformation typically proceeds in excellent yields, employs conveniently available reagents, and produces water as the only byproduct.
Copper-Catalyzed Oxidative Alkylation (Methylation) of Phosphonamides and Phosphinamides Using Dicumyl Peroxide
Xiao, Jing,Su, Qiong,Dong, Wanrong,Peng, Zhihong,Zhang, Yingjun,An, Delie
, p. 9497 - 9504 (2017/09/23)
An effective and practical CuI-catalyzed methodology toward N-alkyl or N-methyl phosphonamides and phosphinamides was herein demonstrated. The transformation took place readily under the oxidative conditions, and plenty of N-alkylated (methylated) amides
Synthesis of nonsymmetrical dialkylamines on the basis of diphenylphosphinic amides
Bondarenko,Kharlamov,Vendilo
experimental part, p. 1872 - 1885 (2011/01/06)
A facile method for the synthesis of nonsymmetrical dialkylamines (C nH2n+1)2NH (n = 1-12) using the Ph 2P(O) protecting group was developed. The method includes successive transformation of monoalkylamines to primary diphenylphosphinic N-alkylamides Ph2P(O)NHR' (R' = CnH2n+1, n = 1-12) by the Todd-Atherton reaction, phase transfer N-alkylation of these compounds, and hydrolysis of the secondary amides Ph2P(O)NR'R″ thus formed. When the (EtO)2P(O) and Bu2P(O) protecting groups are used, N-alkylation of primary amides is accompanied by the formation of Et-O and P-N bond cleavage products, respectively. A study of the stability of the N-alkylamides R2P(O)NHR' (R = Ph, p-MeC6H4, p-CIC6H4, Bu) under strong alkaline conditions used in the phase transfer N-alkylation showed that an increase in the electron-donating ability of substituents at both the nitrogen atom and the phosphorus atom results in a decrease in the degree of P-N bond cleavage. The primary and secondary diphenylphosphinic amides containing a β-hydroxyethyl group at the nitrogen atom are extremely unstable under the alkaline conditions and are converted quantitatively to the diphenylphosphinic acid salt.
Base-induced Rearrangement of Tetraalkyl(diphenylphosphinoyl)hydrazinium Salts to Phosphinyl Aminals; Possible Relevance to the Photochemical Rearrangement of Trialkylammonio(diphenylphosphinoyl)imides
Freeman, Sally,Harger, Martin J. P.
, p. 3257 - 3261 (2007/10/02)
The phosphinoylhydrazinium salt Ph3P(O)N(Me)N+Me3 I- 8 has been prepared by methylation of Ph2P(O)N--N+Me3 1.It readily forms the phosphinoyl aminal Ph2P(O)N(Me)CH2NMe2 10 on treatment with ButOK at room tempera
