25562-98-5

Usage

Uses

Used in Chemical Synthesis:
2-Phenoxyphenylacetonitrile is used as an intermediate in the synthesis of various chemical compounds, particularly in the pharmaceutical and agrochemical industries. Its unique structure allows for the creation of a wide range of derivatives, making it a valuable building block for the development of new molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Phenoxyphenylacetonitrile is used as a key component in the production of certain drugs. Its versatility in chemical reactions enables the creation of new drug candidates with potential therapeutic applications.
Used in Agrochemical Industry:
2-Phenoxyphenylacetonitrile is also employed in the agrochemical industry, where it serves as a precursor for the synthesis of various pesticides and other agricultural chemicals. Its role in the development of these products is crucial for enhancing crop protection and yield.
Used in Material Science:
In the field of material science, 2-Phenoxyphenylacetonitrile is used as a component in the development of new materials with specific properties. Its incorporation into polymers and other materials can lead to the creation of materials with improved characteristics, such as enhanced stability or increased reactivity.

InChI:InChI=1/C14H11NO/c15-11-10-12-6-4-5-9-14(12)16-13-7-2-1-3-8-13/h1-9H,10H2

Upstream product

• 5888-53-9 2-phenoxybenzyl chloride 
• 143-33-9 sodium cyanide 
• 108-90-7 chlorobenzene 
• 446-52-6 2-Fluorobenzaldehyde 
• 108-95-2 phenol 
• 773837-37-9 sodium cyanide 
• 41755-76-4 ethyl 2-phenoxybenzoate 
• 88-67-5 2-Iodobenzoic acid 
• 33838-32-3 potassium 2-formylphenolate 
• 19434-34-5 2-(phenoxy)benzaldehyde 
• 2243-42-7 2-phenoxybenzoic acid 
• 13807-84-6 (2-phenoxyphenyl)methanol 

Downstream Products

• 139995-89-4 α-hydroxyimino-2-phenoxyphenylacetonitrile 
• 1580001-09-7 5-(2-phenoxybenzyl)-2H-1,2,4-triazole-3(4H)-thione 
• 1580001-12-2 5-(2-phenoxybenzyl)-3-methylthio-4H-1,2,4-triazole 
• 1580001-14-4 5-(2-phenoxybenzyl)-3-ethylthio-4H-1,2,4-triazole 
• 1580001-15-5 5-(2-phenoxybenzyl)-3-propylthio-4H-1,2,4-triazole 
• 1580001-16-6 5-(2-phenoxybenzyl)-3-benzylthio-4H-1,2,4-triazole 
• 1417512-55-0 ethyl 2-(2-phenoxyphenyl)acetate 
• 159731-09-6 2-(2-phenoxyphenyl)acetic acid hydrazide 
• 1580001-29-1 2-amino-5-(2-phenoxybenzyl)-1,3,4-oxadiazole 
• 1580001-32-6 5-ethoxy-3-(2-phenoxybenzyl)-4H-1,2,4-triazole 
• 128039-27-0 5-(p-methoxyphenyl)benzoxepine 
• 144836-66-8 5-bromo-6-(p-methoxyphenyl)dibenzoxepine 

Relevant academic research and scientific papers

HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME

Provided in the present invention are a heterocyclic compound and an organic light emitting device comprising the same. Provided in the present invention is a heterocyclic compound presented by following chemical formula 1. The heterocyclic compound according to embodiments of the present invention has a proper energy level, and has excellent electrochemical stability and thermal stability. Therefore, an organic light emitting device including the compound provides high efficiency and/or high driving stability.

Synthesis of targeted dibenzo[b,f]thiepines and dibenzo[b,f]oxepines as potential lead molecules with promising anti-breast cancer activity

A targeted library of substituted dibenzo[b,f]thiepines and dibenzo[b,f]oxepines (prototypes I, II and III), and structurally analogous to tamoxifen have been synthesized as a new class of anti-breast cancer agents. All the prototype molecules exhibited potential antiproliferative activity against ER + ve and ER-ve breast cancer cell lines. Dibenzo[b,f]thiepine prototypes were found to be more active. Of all the compound tested, 14b exhibited potent in-vitro antiproliferative activity at 1.33 μM and 5 μM concentration in MCF-7 and MDA-MB-231 cell lines and was devoid of any cytotoxicity in normal HEK cells even at 50 μM. Cell cycle analysis showed that the compound 14b inhibited cell proliferation due to G0/G1 arrest in MCF-7 cells. Annexin-V FITC and PI staining experiments confirmed that the cell inhibition was primarily due to apoptosis and not by necrosis, which was also supported by LDH release assay experiment. Molecular docking studies showed better binding interaction of the new dibenzo[b,f]thiepine analogue 14b with the estrogen receptor (ER) as compared to 4-hydroxy-tamoxifen and this enhanced binding might be responsible for its estrogen antagonistic activity that induces cell cycle arrest, apoptosis and inhibition of breast cancer cells.

Synthesis, receptor affinity and effect on pentylenetetrazole-induced seizure threshold of novel benzodiazepine analogues: 3-Substituted 5-(2-phenoxybenzyl)-4H-1,2,4-triazoles and 2-amino-5-(phenoxybenzyl)-1,3,4- oxadiazoles

The new series of 5-(2-phenoxybenzyl)-4H-1,2,4-triazoles, possessing C-3 thio, alkylthio and ethoxy substituents, and 2-amino-5-(2-phenoxybenzyl)-1,3,4- oxadiazoles were designed and synthesized as novel benzodiazepine analogues. Most of them revealed sim

Synthesis of the Polycyclic Ring Systems of Artocarpol A and D

(Equation Presented) The first synthesis of the polycyclic ring systems of artocarpol A and D has been accomplished. These natural products were isolated recently from the root bark of Artocarpus rigida, and artocarpol A has been shown to have potent anti

Substituted (2-Phenoxyphenyl)acetic Acids with Antiinflammatory Activity. 1

The synthesis and antiinflammatory activity of a series of substituted (2-phenoxyphenyl)acetic acids are described.Initial screening in the adjuvant arthritis test showed that halogen substitution in the phenoxy ring enhanced activity considerably.Ulcerogenic potential, as measured by the minimum ulcerogenic dose (MUD), was low in almost all the acids tested. acetic acid possessed the most favorable combination of potency with low toxicity, including ulcerogenicity, and this compound is now in therapeutic use.