2562-89-2Relevant academic research and scientific papers
One-pot chemo/regio/stereoselective generation of a library of functionalized spiro-oxindoles/pyrrolizines/pyrrolidines from α-aroylidineketene dithioacetals
Dhanalakshmi, Pandi,Babu, Seenivasagaperumal Sriram,Thimmarayaperumal, Solaimalai,Shanmugam, Sivakumar
, p. 33705 - 33719 (2015)
An efficient chemo/regio/stereoselective synthesis of novel and functionalized spiro-oxindole/pyrrolizine/pyrrolidine scaffolds has been achieved. The in situ generated azomethine ylide from isatin & l-proline/phenyl alanine underwent 1,3-dipolar cycloadd
Microwave-assisted solvent-free synthesis of some styryl dyes with benzimidazole nucleus
Wang, Lanying,Zhang, Xiaogang,Li, Fengmei,Zhang, Zuxun
, p. 2245 - 2252 (2007/10/03)
A series of styryl dyes: 2-substituted styryl benzimidazole and α-methyl-2-substituted styryl benzimidazole were synthesized under solvent-free microwave irradiation by the condensation of 2-methylbenzimidazole or 2-ethylbenzimidazole with aromatic aldehydes in the presence of Ac 2O.
2-Aryl-substituted benzo-anellated 5-membered heterocycles as potential effectors in the cardiovascular system. Part 2
Rose
, p. 775 - 777 (2007/10/02)
In the course of investigations on structure-activity relationships of fostedil-and sulmazole-analoguesly fused 5-membered heterocycles, 1,3-benzimidazoles were obtained by simple cyclisation. In vitro experiments on isolated organs demonstrate markedly positive inotropic effects of some derivatives, whereas others exert both relaxing activity on smooth musculature in vitro and antihypertensive effects in vivo. Moreover they exhibit fungicide properties in vitro.
Application of Phase-Transfer Catalysis to the Synthesis of Mono- and Bis-stilbenes and Styryls
Lokhande, S. B.,Rangnekar, D. W.
, p. 485 - 488 (2007/10/02)
A novel and convenient method has been developed for the synthesis of substituted stilbenes by the condensation of active methyl group in suitably substituted toluenes with aromatic aldehydes in aq. medium at room temperature using benzyltriethylammonium chloride as a phase-transfer catalyst.This method has also been applied for the preparation of heterocyclic styryls and extended to the synthesis of bis-stilbenes and bis-styryls using aromatic dialdehydes in place of monoaldehydes.A comparison of the results shows that the present method is superior to the conventional methods in many respects.
