25632-60-4Relevant academic research and scientific papers
Synthesis and evaluation of aromatic methoxime derivatives against five postharvest phytopathogenic fungi of fruits. Main structure–activity relationships
Cortés, Iván,di Liberto, Melina G.,Kaufman, Teodoro S.,Derita, Marcos G.,Bracca, Andrea B.J.
, (2020/04/15)
The antifungal activity of a library of twenty-four aromatic methoximes was examined against five representative postharvest phytopathogenic fungi. The panel included Penicillium digitatum, Penicillium italicum, Rhizopus stolonifer, Botrytis cinerea and Monilinia fructicola, all of which cause relevant economic losses worldwide as a result of affecting harvested fruits. The minimum inhibitory concentrations and minimum fungicidal concentrations of each compound were defined and the main structure–activity relationships were determined. Although other congeners were more potent, drug likeliness considerations pointed to the methoxime derived from 2,4-dihydroxypropiophenone as the compound with the most suitable profile. The morphology of the colonies of the fungal strains treated with the methoxime was examined microscopically and the compound was also tested in freshly harvested peaches and oranges, exhibiting promising control profiles in both fruits, similar to those of the commercial agents Imazalil and Carbendazim.
ANTIBACTERIAL AGENTS AGAINST DRUG-RESISTANT STAPHYLOCOCCUS AUREUS OR VANCOMYCIN-RESISTANT ENTEROCOCCUS AND ANTIFUNGAL AGENTS COMPRISING STEPHANITIS SVENSONI-DERIVED POLYKETIDE OR SYNTHETIC ANALOGS THEREOF
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Paragraph 0036-0038, (2020/10/27)
PROBLEM TO BE SOLVED: To provide antibacterial or antifungal agents comprising a naturally occurring substance or synthetic analogs thereof having high antibacterial activity against methicillin-resistant Staphylococcus aureus or vancomycin-resistant Ente
Lipase-catalysed regio- and enantioselective deacetylation of 2,4-diacetoxyphenyl alkyl ketones
Prasad, Ashok K.,Pati, Hari N.,Azim, Abul,Trikha, Smriti,Poonam
, p. 1973 - 1977 (2007/10/03)
Porcine pancreatic lipase in tetrahydrofuran catalyses the deacetylation of 2,4-diacetoxyphenyl alkyl ketones in a highly regioselective fashion. The strategy of regioselective deacetylation of diacetoxyphenyl alkyl ketones has also resulted in the enanti
Synthese von 4-Alkoxy-2-hydroxyphenylketoximen als Metallextraktions-Reagenzien
Beger, J.,Binte, H.-J.,Brunne, L.,Neumann, R.
, p. 269 - 277 (2007/10/02)
The C-Acylation (Friedel-Crafts reaction) of resorcinol with aluminium chloride, the monoetherification in 4-position of the resulting 2,4-dihydroxyphenylketones, and the preparation of oximes (8, 9, 10, 11) from this ketones were investigated.The compounds obtained are characterized by elemental analysis, and the i.r., u.v. and 1H-n.m.r. spectra are discussed.Solubility data of some oximes are determined in water, octane and toluene.The extraction properties for copper-(II)-and iron-(III)-ions are measured by isotope methods in relation to the extragent structure, the extraction time and the pH-range.
