256347-45-2

Upstream product

• 256347-41-8 (S)-2-Amino-N-(3-cyclohexyl-propyl)-N-methyl-butyramide 
• 256347-44-1 5-(2-tert-butoxycarbonylamino-2-carboxy-ethyl)-2-[(diethoxy-phosphoryl)-difluoro-methyl]-benzoic acid methyl ester 
• 14192-13-3 methyl 2,5-diiodobenzoate 
• 14192-12-2 2,5-diiodobenzoic acid 

Downstream Products

• 256347-47-4 {[4-((S)-2-Acetylamino-2-{(S)-1-[(3-cyclohexyl-propyl)-methyl-carbamoyl]-propylcarbamoyl}-ethyl)-2-hydroxymethyl-phenyl]-difluoro-methyl}-phosphonic acid diethyl ester 
• 256347-46-3 5-((S)-2-Acetylamino-2-{(S)-1-[(3-cyclohexyl-propyl)-methyl-carbamoyl]-propylcarbamoyl}-ethyl)-2-[(diethoxy-phosphoryl)-difluoro-methyl]-benzoic acid methyl ester 
• 256347-48-5 {[4-((S)-2-Acetylamino-2-{(S)-1-[(3-cyclohexyl-propyl)-methyl-carbamoyl]-propylcarbamoyl}-ethyl)-2-formyl-phenyl]-difluoro-methyl}-phosphonic acid diethyl ester 

Relevant academic research and scientific papers

An efficient synthesis of a 4'-phosphonodifluoromethyl-3'-formyl-phenylalanine containing Src SH2 ligand

A CuBr-mediated, regioselective cross-coupling between methyl 2,5-diiodobenzoate (4) and [(diethoxyphosphinyl)difluoromethyl]zinc bromide is reported. Palladium-catalyzed incorporation of an amino acid side chain, followed by subsequent modifications resu