2564-09-2

Basic information

• Product Name: N-(p-Tolyl)trichloroacetamide
• Synonyms: 2,2,2-Trichloro-N-(4-methylphenyl)acetamide;N-(p-Tolyl)trichloroacetamide;4'-METHYL-2,2,2-TRICHLOROACETANILIDE
• CAS NO: 2564-09-2
• Molecular Formula: C₉H₈Cl₃NO
• Molecular Weight: 252.52
• Mol File: 2564-09-2.mol

Chemical Properties

• Boiling Point: 336°C at 760 mmHg
• Flash Point: 157°C
• Appearance: /
• Density: 1.459g/cm³
• Vapor Pressure: 0.000115mmHg at 25°C
• Refractive Index: 1.608
• CAS DataBase Reference: N-(p-Tolyl)trichloroacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(p-Tolyl)trichloroacetamide(2564-09-2)
• EPA Substance Registry System: N-(p-Tolyl)trichloroacetamide(2564-09-2)

Safety Data

• Hazardous Substances Data: 2564-09-2(Hazardous Substances Data)

Usage

Uses

Used in Agricultural Industry:
N-(p-Tolyl)trichloroacetamide is used as a pesticide for controlling a wide range of pests and insects that can damage crops and reduce agricultural productivity. Its application helps protect crops from infestations, ensuring a healthy and sustainable yield.
Used in Industrial Settings:
In industrial applications, N-(p-Tolyl)trichloroacetamide serves as a pest control agent, particularly in areas where infestations can cause damage to infrastructure or pose health risks. Its targeted action on pests and low toxicity to non-target organisms make it suitable for use in various industrial environments.
It is important to follow proper handling and application procedures when using N-(p-Tolyl)trichloroacetamide to minimize potential risks and ensure its effectiveness in pest control.

InChI:InChI=1/C9H8Cl3NO/c1-6-2-4-7(5-3-6)13-8(14)9(10,11)12/h2-5H,1H3,(H,13,14)

Upstream product

• 116-16-5 1,1,1,3,3,3-hexachloro-propan-2-one 
• 106-49-0 p-toluidine 
• 76-02-8 trifluoroacetyl chloride 
• 76-03-9 trichloroacetic acid 

Downstream Products

• 3299-61-4 N,N'-Di-p-tolyloxalamide 
• 83785-31-3 N-phenyl-N'-p-tolyl-oxalamide 
• 5255-84-5 5-(phenoxymethyl)-3-(p-tolyl)oxazolidin-2-one 
• 5602-96-0 methyl p-tolylcarbamate 
• 80945-63-7 methyl 2-oxo-2-(p-tolylamino)acetate 
• 106-49-0 p-toluidine 
• 122778-78-3 3-(5-Methyl-2-trichloracetylaminophenyl)-2-phenylcyclopropenon 
• 73108-78-8 6-methyl-3-phenylquinolin-2(1H)-one 
• 122778-81-8 3-(2-Amino-5-methylphenyl)-2-phenylcyclopropenon 
• 122778-96-5 1-Phenyl-2-(2-trichloracetylamino-5-methylphenyl)ethin 
• 1018222-97-3 N-(4-methylphenyl)-N'-(6-chlorobenzothiazol-2-yl)urea 
• 444932-33-6 N-(4-methylphenyl)-N'-(6-nitrobenzothiazol-2-yl)urea 

Relevant articles and documents

A novel synthesis of isocyanates and ureas via β-elimination of haloform

A novel synthesis of isocyanates via base-induced β-elimination of haloform from N-monosubstituted trihaloacetamides is described. The rate of reaction exhibits a strong dependence on the nature of the trihalomethyl group. Thus, while the reaction of tribromoacetamides proceeds at room temperature and the reaction of trichloroacetamides requires heating in polar solvents, no reaction could be observed for any of the corresponding trifluoro derivatives. This novel β-elimination of haloform from stable and readily available trihaloacetamides was applied to a 'one-pot' synthesis of ureas which avoids the use of phosgene and isolation of isocyanates.

Formation of N-Substituted Trichloroacetamides from Amines and Hexachloroacetone

Procedures are described for converting primary amines into their well-crystalline trichloroacetyl-derivatives by treatment with hexachloroacetone under mild conditions.Although secondary aromatic N-methylamines are unaffected by hexachloroacetone, saturated heterocyclic amines react vigorously.A mechanistic study using 2-amino-4-t-butylthiazole showed that the reaction is first order in hexachloroacetone, second order in amine, and base-catalysed; there is no appreciable kinetic isotope (H/D) effect nor accumulation of intermediates during the reaction.A sequence which accommodates these results is suggested.