3299-61-4

Basic information

• Product Name: N,N'-Bis(4-methylphenyl)oxamide
• Synonyms: N,N'-Bis(4-methylphenyl)oxamide;p-Oxalotoluidide;N,N'-Bis(4-Methylphenyl)ethanediaMide;N1,N2-Bis(4-Methylphenyl)ethanediaMide;NSC 401961
• CAS NO: 3299-61-4
• Molecular Formula: C₁₆H₁₆N₂O₂
• Molecular Weight: 268.3104
• Product Categories: Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 3299-61-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.241g/cm³
• CAS DataBase Reference: N,N'-Bis(4-methylphenyl)oxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-Bis(4-methylphenyl)oxamide(3299-61-4)
• EPA Substance Registry System: N,N'-Bis(4-methylphenyl)oxamide(3299-61-4)

Safety Data

• Hazardous Substances Data: 3299-61-4(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 3299-61-4 differently. You can refer to the following data:
1. A N,N’-diarylalkanediamide
2. A N,N’-diarylalkanediamide having antimycobacterial and antialgal activity. A new group of potential tuberculostatics.

Upstream product

• 102878-71-7 2-hydroxy-N-(4-methylphenyl)acetamide 
• 157368-88-2 1,2-Bisethan-1,2-diamin 
• 98831-16-4 p-Toluidinium-oxalat 
• 3155-16-6 diphenyl oxalate 
• 17450-22-5 bis(4-methylphenylamino)methane 
• 79-37-8 oxalyl dichloride 
• 106-49-0 p-toluidine 
• 1677-44-7 4-hydroxy-6-methylquinolin-2(1H)-one 
• 64-19-7 acetic acid 
• 10026-13-8 phosphorus pentachloride 
• 71-43-2 benzene 
• 144217-52-7 N-(4-methylphenyl)-2-(4-methylphenylamino)-2-thioxoacetamide 
• 7722-84-1 dihydrogen peroxide 
• 123-91-1 1,4-dioxane 

Downstream Products

• 7472-70-0 N,N'-bis(4-methylphenyl)ethanediimidoyl dichloride 
• 1225042-68-1 [(pentamethylcyclopentadienyl)2Rh2Cl2(μ-N,N'-bis(4-methylphenyl)oxamidato)] 
• 1225042-66-9 [(pentamethylcyclopentadienyl)2Ir2Cl2(μ-N,N'-bis(4-methylphenyl)oxamidato)] 
• 1196680-82-6 [(p-cymene)2Ru2(μ-N,N'-bis(p-tolyl)oxamidato)Cl2] 
• 144217-52-7 N-(4-methylphenyl)-2-(4-methylphenylamino)-2-thioxoacetamide 
• 52426-98-9 N,N'-bis-(4-methyl-2-nitro-phenyl)-oxalamide 
• 608-05-9 5-methyl-indole-2,3-dione 

Relevant articles and documents

Tuning the Reactivity of Cofacial Porphyrin Prisms for Oxygen Reduction Using Modular Building Blocks

We assembled eight cofacial porphyrin prisms using MTPyP (M = Co(II) or Zn(II), TPyP = 4-tetrapyridylporphyrin) and functionalized ruthenium-based "molecular clips"using coordination-driven self-assembly. Our approach allows for the rapid synthesis of these architectures in isolated yields as high as 98% for the assembly step. Structural and reactivity studies provided a deeper understanding of the role of the building blocks on the oxygen reduction reaction (ORR). Catalytic efficacy was probed by using cyclic and hydrodynamic voltammetry on heterogeneous catalyst inks in aqueous media. The reported prisms showed outstanding selectivity (>98%) for the kinetically hindered 4e-/4H+ reduction of O2 to H2O over the kinetically more accessible 2e-/2H+ reduction to H2O2. Furthermore, we have demonstrated significant cofacial enhancement in the observed catalytic rate constant ks (μ5 orders of magnitude) over the mononuclear analogue. We conclude that the steric bulk of the clip plays an important role in the structural dynamics of these prisms, which in turn modulates the ORR reactivity with respect to selectivity and kinetics.

A convenient synthesis of oxazolo[3,2-a]quinolones

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SmI2 Promoted Coupling Reaction of Isocyanates to Oxamides

Oxamides were obtained in moderate to good yields by the reaction of isocyanates with the SmI2/HMPA/THF system under mild conditions.The system also caused desulfurization of isothiocyanates to give isocyanides in good yields.