2564-56-9

Upstream product

• 104-85-8 para-methylbenzonitrile 
• 2485-62-3 L-Cysteine methyl ester 
• 827-71-4 4-methyl-benzimidic acid ethyl ester 
• 18598-63-5 L-cysteine methyl ester hydrochloride 
• 56108-06-6 p-toluimidic acid methyl ester 
• 1196463-53-2 (R)-2-(4-methylphenyl)-4,5-dihydrothiazole-4-carboxylic acid 
• 74-88-4 methyl iodide 
• 3235-02-7 p-methylbenzaldehyde oxime 
• 104-87-0 4-methyl-benzaldehyde 
• 1174307-93-7 C₁₁H₁₁NO₂S 

Downstream Products

• 1315510-09-8 methyl 2-(4-methylphenyl)thiazole-4-carboxylate 
• 1315510-24-7 dimethyl 2,2'-di-(4-methylphenyl)-bis-5,5'-thiazole-4,4'-dicarboxylate 
• 1370731-41-1 methyl 2-(p-methylphenyl)-5-phenylthiazole-4-carboxylate 

Relevant academic research and scientific papers

Cu(i)-Catalyzed oxidative homo-coupling of thiazoline-4-carboxylates: Synthesis of 4,4′-bithiazoline derivatives

Cu(i)-Catalyzed oxidative homo-coupling of thiazoline-4-carboxylates with good functional group tolerance has been developed. The methodology presented an efficient method to directly construct vicinal carbon-hetero quaternary centers existing in numerous functional molecules and could be applied to the synthesis of 4,4′-bithiazoles which are difficult to prepare by direct C-H activation.

Pd(ii)-catalyzed direct C5-arylation of azole-4-carboxylates through double C-H bond cleavage

The first palladium-catalyzed direct C5-arylation of azole-4-carboxylates with simple unactivated arenes through double C-H bond cleavage is realized. This protocol provided a straightforward access to diverse 5-arylsubstituted azole-4-carboxylic derivatives with good functional group tolerance. The Royal Society of Chemistry 2012.