256464-87-6

Upstream product

• 6737-11-7 2-acetoxy-3-butene 
• 4541-14-4 4-benzyloxy-butan-1-ol 
• 5470-84-8 4-benzyloxybutanal 
• 100-39-0 benzyl bromide 
• 624-64-6 trans-2-Butene 
• 99687-40-8 (R,R)-[(E)-2-butenyl]diisopropyl tartrate boronate 

Downstream Products

• 115566-02-4 bistramide A 
• 887612-26-2 2-{3-[(2R,3S,6S,8S)-8-[(S)-4-(tert-butyldiphenylsilyloxy)-3-methylbutyl]-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]propyl}isoindoline-1,3-dione 
• 887612-10-4 3-((2R,3S,6S,8S)-8-[(S)-4-(tert-butyldiphenylsilyloxy)-3-methylbutyl]-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl)propan-1-ol 
• 887612-21-7 C₂₂H₂₆Br₂O₂ 
• 887612-09-1 C₂₂H₂₆O₂ 
• 256464-93-4 C₃₂H₄₂O₄ 
• 256464-92-3 C₃₂H₄₀O₃ 
• 256464-91-2 C₂₅H₃₄O₃ 
• 256464-97-8 C₃₃H₄₄O₄ 
• 256464-96-7 C₃₃H₄₂O₄ 
• 256464-95-6 C₃₃H₄₁NO₃ 
• 256464-94-5 C₃₉H₄₈O₆S 
• 256464-89-8 (3S,4R)-4,7-Bis-benzyloxy-3-methyl-heptane-1,2-diol 
• 256464-90-1 (2R,3R)-3,6-Bis-benzyloxy-2-methyl-hexanal 

Relevant academic research and scientific papers

Anti-diastereo-and enantioselective carbonyl crotylation from the alcohol or aldehyde oxidation level employing a cyclometallated iridium catalyst: α-methyl allyl acetate as a surrogate to preformed crotylmetal reagents

Under the conditions of transfer hydrogenation employing an ortho-cyclometallated iridium catalyst generated in situ from [Ir(cod)Cl] 2, 4-cyano-3-nitrobenzoic acid and the chiral phosphine ligand (S)-SEGPHOS, α-methyl allyl acetate couples to

Enantioselective total synthesis of bistramide A

The enantioselective synthesis of bistramide A has been achieved with a longest linear sequence of 18 steps. The synthetic strategy involves the use of a distereoselective glycolate alkylation, an aldol addition of a chlorotitanium enolate of N-acylthiazolidinthione, and a Sharpless asymmetric epoxidation to synthesize the three key fragments. Copyright

A stereocontrolled synthetic route to the C1-C18 subunit of pamamycin-607

The C1-C18 subunit 2 of the 16-membered macrodiolide pamamycin-607 has been synthesized stereoselectively using the Ag2CO3-mediated intramolecular iodoetherification for the two cis-2,5-disubstituted tetrahydrofurans, crotylation and cuprate epoxide opening for the hydroxyl and methyl substituents.

Toward creation of a universal NMR database for the stereochemical assignment of acyclic compounds: Proof of concept

Oasomycin B: R = α-D-mannosyl Using the C.5-C.10 portion of the oasomycin class of natural products, the reliability and usefulness of an NMR database for the stereochemical assignment of acyclic compounds has been demonstrated. The predicted relative stereochemistry based on the NMR database has unambiguously been established via synthesis.