25654-51-7

Usage

Uses

Used in Pharmaceutical Research and Development:
(R)-N-CBZ-AZETIDINE-2-CARBOXYLIC ACID is used as a building block in the synthesis of complex organic molecules for its unique structural and chemical properties, contributing to the advancement of new drug candidates.
Used in Organic Synthesis:
(R)-N-CBZ-AZETIDINE-2-CARBOXYLIC ACID is employed as a key intermediate in the creation of intricate organic compounds, facilitating the development of novel chemical entities with potential applications across various industries.
Used in Materials Science:
(R)-N-CBZ-AZETIDINE-2-CARBOXYLIC ACID is used as a precursor for the synthesis of novel materials, potentially leading to breakthroughs in material properties and functionalities.
Used in Drug Discovery:
(R)-N-CBZ-AZETIDINE-2-CARBOXYLIC ACID is utilized in the exploration of new therapeutic agents, capitalizing on its potential biological activity for the treatment of various diseases and conditions.

Upstream product

• 501-53-1 benzyl chloroformate 
• 7729-30-8 (R)-azetidine-2-carboxylic acid 
• 174740-81-9 N-benzyloxycarbonyl-(S)-(-)-2-azetidine-carboxylic acid 

Downstream Products

• 144062-01-1 (R)-Azetidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester 
• 7729-30-8 (R)-azetidine-2-carboxylic acid 
• 144062-02-2 (R)-2-(Hydroxy-diphenyl-methyl)-azetidine-1-carboxylic acid benzyl ester 
• 144062-03-3 (R)-4,4-Diphenyl-3-oxa-1-aza-bicyclo[3.2.0]heptan-2-one 
• 174740-83-1 (R)-1-(benzyloxycarbonyl)-3-((2-azetidynylmethyl)oxy)pyridine 

Relevant academic research and scientific papers

3-Pyridyl enantiomers and their use as analgesics

The present invention relates to a method of controlling pain in mammals, including humans, comprising administering to a mammal or patient in need of treatment thereof selected compounds of formula I: STR1 or a pharmaceutically acceptable salt thereof. The invention further relates to selected (R) and (S) compounds of formula I above which are useful as analgesics as well as neuronal cell death preventors and anti-inflammatories.

Aldehyde derivatives and their use as calpain inhibitors

Aldehyde derivatives with a specific calpain inhibiting activity and a platelet-aggregation inhibiting effect with formula (I) or formula (II): wherein R1 represents an aromatic hydrocarbon group, a heterocyclic group, or a group of-X-R3 in which X represents O,-S(O)m-(m = 0, 1, or 2), and R3 represents an aromatic hydrocarbon group, a heterocyclic group, or an alkyl group; Z represents R?-Y-or R?O-CH(R?)-in which Y represents a 3-to 7-membered nitrogen-containing saturated heterocyclic group, or a single cyclic saturated hydrocarbon group, R? represents an alkyl group, an alkenyl group, an alkynyl group, an acyl group, a sulfonyl group, an alkoxycarbonyl group, a carbamoyl group, or a thiocarbamoyl group, R? represents hydrogen, an alkyl group, or an aromatic hydrocarbon group, and R? represents an acyl group, a carbamoyl group, a thiocarbamoyl group, or an alkyl group; and n is an integer of 1 to 5. wherein R?, R?, R?, and R1? are defined in the specification.

Enantioselective catalytic reductions of ketones with new four membered oxazaborolidines: Application to (S)-tetramisole

Enantioselective catalytic reduction of ketones with both the enantiomers of new four membered oxazaborolidines is described.