2566-48-5Relevant articles and documents
Absolute Configuration of Optically Active Tricyclo2,6>heptan-3-ol (Nortricyclanol). An Enhancement of Enantiomeric Purity of a Chiral Alcohol by Repeating Enzymatic Kinetic Resolution
Hirose, Yoshiki,Anzai, Mika,Saitoh, Minoru,Naemura, Koichiro,Chikamatsu, Hiroaki
, p. 1939 - 1942 (2007/10/02)
Tricyclo2,6>hept-3-yl acetate (1b) was resolved by repeated enantioselective hydrolysis catalyzed by Candida Cylindracea lipase, to give (+)-1b and (-)-nortricyclanol (1a) in high enantiomeric excess.By the chemical correlation with the known exo-2-norbornanol, the absolute configuration of (-)-1a was assigned to be (1R,3S,6S).