256659-01-5

Upstream product

• 256658-99-8 (+)-[2S,4S,R(S)]-6-hydroxy-syn-2,4-(isopropylidenedioxy)-1-(p-tolylsulfinyl)hexane 
• 182219-57-4 methyl (+)-(SR)-3,5-dioxo-6-(p-toluenesulfinyl)hexanoate 
• 171523-69-6 (+)-<3(R),5(S),S(R)>-Methyl syn-3,5-(isopropylidenedioxy)-6-(p-tolylsulfinyl)hexanoate 
• 171523-68-5 (+)-<3(R),5(S),S(R)> methyl 3,5-dihydroxy-6-(p-tolylsulfinyl) hexanoate 
• 77-76-9 2,2-dimethoxy-propane 
• 1517-82-4 (1R,2S,5R,SS)-(-)-menthyl p-toluenesulfinate 
• 108-24-7 acetic anhydride 
• 256659-00-4 (+)-[2S,4S,S(R)]-6-benzyloxy-syn-2,4-(isopropylidenedioxy)-1-(p-tolylsulfinyl)hexane 

Downstream Products

• 106799-15-9 3,5-dideoxy-2,4-O-(1-methylethylidene)-6-O-(phenylmethyl)-L-erythro-hexose 
• 256659-02-6 (4R,6S)-4-(2-(benzyloxy)ethyl)-6-ethynyl-2,2-dimethyl-1,3-dioxane 

Relevant academic research and scientific papers

A chiral β,δ-dioxo-ε-sulfinyl ester in a convergent enantioselective synthesis towards the C1-C13 polyol fragment of amphotericin B

This paper describes an efficient stereocontrolled and convergent approach towards the C1-C13 polyol fragment of amphotericin B. The strategy is based on the stereoselective reduction of a chiral β,γ-dioxo- ε-sulfinyl ester to obtain anti-or syn-1,3-diols.