2568-06-1

Basic information

• Product Name: 4,4,6-trimethyl-2-phenyl-1,3-dioxane
• Synonyms: 4,4,6-trimethyl-2-phenyl-1,3-dioxane;1,3-Dioxane,4,4,6-trimethyl-2-phenyl-(9CI);Nsc25466
• CAS NO: 2568-06-1
• Molecular Formula: C₁₃H₁₈O₂
• Molecular Weight: 206.28082
• EINECS: 219-905-9
• Product Categories: PHENYL
• Mol File: 2568-06-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 279.8°C at 760 mmHg
• Flash Point: 129.1°C
• Appearance: /
• Density: 0.977g/cm³
• Vapor Pressure: 0.00667mmHg at 25°C
• Refractive Index: 1.481
• CAS DataBase Reference: 4,4,6-trimethyl-2-phenyl-1,3-dioxane(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4,6-trimethyl-2-phenyl-1,3-dioxane(2568-06-1)
• EPA Substance Registry System: 4,4,6-trimethyl-2-phenyl-1,3-dioxane(2568-06-1)

Safety Data

• Hazardous Substances Data: 2568-06-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H18O2/c1-10-9-13(2,3)15-12(14-10)11-7-5-4-6-8-11/h4-8,10,12H,9H2,1-3H3

Upstream product

• 107-41-5 2-methyl-2,4-pentanediol 
• 100-52-7 benzaldehyde 

Downstream Products

• 96556-34-2 4-(benzyloxy)-4-methyl-2-pentanol 
• 77743-40-9 4-methyl-2-pentyl benzoate 
• 109789-35-7 (2R,6R)-4,4,6-Trimethyl-2-o-tolyl-[1,3]dioxane 

Relevant articles and documents

A Direct Method for the Efficient Synthesis of Benzylidene Acetal at Room Temperature

For the first time, a metal-free direct method has been developed for the efficient synthesis of benzylidene acetal at room temperature using Dowex 50WX8 as a solid acid catalyst and Cl3CCN as a novel water scavenger. At room temperature, a wide variety of aryl and α,β-unsaturated aldehydes react readily with functionalized 1,2- and 1,3-diols to furnish the corresponding acetals in very good yields. Labile functional groups, like N-Boc, N-Cbz, -OTBDMS, -OBn, -N3 and acetonide are found to be stable under the reaction conditions. The versatility of this method is further demonstrated with carbohydrate substrates and optically active diols.