257290-71-4Relevant academic research and scientific papers
2-Sulfonyliminodihydropyrimidines: A novel class of analgesic compounds
Gonzalez-Rosende, M. Eugenia,Olivar, Teresa,Castillo, Encarna,Sepulveda-Arques, Jose
experimental part, p. 690 - 695 (2009/04/06)
A series of 2-sulfonyliminodihydropyrimidine derivatives have been synthesized and evaluated in vivo for their antinociceptive and anti-inflammatory activities. The results were compared with that of acetyl salicylic acid. Compounds 6Ab-d and 6Be displaye
Unusual ring closure reaction of amides with pyrimidines: Novel stereoselective synthesis of hexahydroimidazo[1,2-c]pyrimidines
Acero-Alarcoì?n, Alberto,Armero-Alarte, Trinidad,Jorda-Gregori, Joan M.,Rojas-Argudo, Cristina,Zaballos-Garciì?a, Elena,Server-Carrioì?, Juan,Ahjyaje, Fatima Z.,Sepulveda-Arques, Joseì?
, p. 2124 - 2130 (2007/10/03)
Hexahydromidazo[1,2-c]pyrimidines 6 were prepared by the reaction of tosylpyrimidines 2 with bromoacetamides 3 in one step. The stereoselectivity of the reaction has been confirmed by X-ray analysis. Imidazo[1,2- a]pyrimidines 5 were obtained on heating h
