25752-17-4Relevant articles and documents
Imidazothiazole Derivatives or Its Pharmaceutically Acceptable Salts and Pharmaceutical Use Thereof
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, (2017/05/10)
The present invention relates to a novel imidazothiazole compound for inhibiting an NF-andkappa;B activity, and to a medical use thereof. More specifically, a novel imidazothiazole derivative according to the present invention has inhibited the generation
Synthesis of 2-phenylimidazo[2,1-b]benzothiazole derivatives as modulators of multidrug resistance for tumor cells
Tasaka, Shigeyuki,Tanabe, Hirokazu,Sasaki, Yoshiyuki,Machida, Toshiki,Iino, Mayumi,Kiue, Akira,Naito, Seiji,Kuwano, Michihiko
, p. 1763 - 1767 (2007/10/03)
We have investigated 3-substituted-2-phenylimidazo[2,1-b]benzothiazole derivatives and herein we have discussed their pharmaceutical activities. We found that some 2-phenyl-5,6,7,8-tetrahydroimidazo[2,1-b]-benzothiazoles could overcome multidrug resistance for tumor cells. Among them, 2-phenyl-3- (N-methyl-3-piperidyl)carbonylaminoiminomethyl-5,6,7,8-tetrahydroimidazo[2,1- b]benzothiazole [N276-12] demonstrated the most potent activity for overcoming multidrug resistance.
Indoline coupled isothiazole azo dyes
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, (2008/06/13)
Disclosed are novel azo dyes containing an isothiazole azo moiety which may be substituted, and a heterocyclic coupler which also may be substituted. The dyes produce yellow shades on, for example, hydrophobic textile fiber including polyesters, polyamide