25752-17-4

Upstream product

• 6857-34-7 4-phenyl-1,3-dihydro-2H-imidazole-2-thione 
• 822-87-7 2-Chlorocyclohexanone 
• 108-94-1 cyclohexanone 
• 2933-29-1 2-Amino-4,5,6,7-tetrahydrobenzothiazole 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 109336-96-1 4-(5,6,7,8-tetrahydro-benz[d]imidazo[2,1-b]thiazol-2-yl)-benzenesulfonic acid 
• 182919-40-0 5,6,7,8-tetrahydro-2-phenyl-3-formylimidazo[2,1-b]benzothiazole 
• 1618656-76-0 3-(3,5-bis(trifluoromethyl)phenyl)-2-phenyl-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole 
• 1618656-77-1 3-(4-nitro-3-(trifluoromethyl)phenyl)-2-phenyl-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole 
• 1618656-72-6 3-(4-nitrophenyl)-2-phenyl-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole 
• 1618656-73-7 3-(3-nitrophenyl)-2-phenyl-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole 
• 1618656-74-8 4-(2-phenyl-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazol-3-yl)benzonitrile 
• 1618656-75-9 2-phenyl-3-(4-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole 
• 202482-77-7 (2-Phenyl-5,6,7,8-tetrahydro-benzo[d]imidazo[2,1-b]thiazol-3-yl)-methanol 

Relevant academic research and scientific papers

Imidazothiazole Derivatives or Its Pharmaceutically Acceptable Salts and Pharmaceutical Use Thereof

The present invention relates to a novel imidazothiazole compound for inhibiting an NF-andkappa;B activity, and to a medical use thereof. More specifically, a novel imidazothiazole derivative according to the present invention has inhibited the generation

Synthesis of 2-phenylimidazo[2,1-b]benzothiazole derivatives as modulators of multidrug resistance for tumor cells

We have investigated 3-substituted-2-phenylimidazo[2,1-b]benzothiazole derivatives and herein we have discussed their pharmaceutical activities. We found that some 2-phenyl-5,6,7,8-tetrahydroimidazo[2,1-b]-benzothiazoles could overcome multidrug resistance for tumor cells. Among them, 2-phenyl-3- (N-methyl-3-piperidyl)carbonylaminoiminomethyl-5,6,7,8-tetrahydroimidazo[2,1- b]benzothiazole [N276-12] demonstrated the most potent activity for overcoming multidrug resistance.

Acid azo dyes containing heterocyclic couplers

Disclosed are novel acid azo dyes containing a sulfonated, sulfated or thiosulfated organothiothiadiazole azo moiety and a heterocyclic coupler which may be substituted. The dyes produce reddish-yellow to orange shades on, for example, hydrophobic textile

Indoline coupled isothiazole azo dyes

Disclosed are novel azo dyes containing an isothiazole azo moiety which may be substituted, and a heterocyclic coupler which also may be substituted. The dyes produce yellow shades on, for example, hydrophobic textile fiber including polyesters, polyamide

Condensed Tetrahydrobenzothiazoles: Part III - Synthesis of 2-Aryl-5,6,7,8-tetrahydroimidazobenzothiazoles and 1,2,3,4-Tetrahydrobenzimidazobenzothiazoles and Their 4/5 Carbethoxy Derivatives

2-Aryl-5,6,7,8-tetrahydroimidazobenzothiazoles (III) have been prepared by the condensation of substituted 2-amino-4,5,6,7-tetrahydrobenzothiazoles (I) with phenacyl bromides (II), while 1,2,3,4-tetrahydrobenzimidazobenzothiazoles (IXa) have