257603-50-2Relevant academic research and scientific papers
J-104129, a novel muscarinic M3 receptor antagonist with high selectivity for M3 over M2 receptors
Mitsuya, Morihiro,Mase, Toshiaki,Tsuchiya, Yoshimi,Kawakami, Kumiko,Hattori, Hiromi,Kobayashi, Kensuke,Ogino, Yoshio,Fujikawa, Toru,Satoh, Akio,Kimura, Toshifumi,Noguchi, Kazuhito,Ohtake, Norikazu,Tomimoto, Koji
, p. 2555 - 2567 (2007/10/03)
A new class of 4-acetamidopiperidine derivatives has been synthesized and investigated for human muscarinic receptor subtype selectivity. Introduction of a hydrocarbon chain of appropriate length into the piperidine nitrogen of the racemic N-(piperidin-4-
