257947-27-6

Basic information

• Product Name: threo-3-phenylisoserineamide
• Synonyms: threo-3-phenylisoserineamide
• CAS NO: 257947-27-6
• Molecular Weight: 180.206
• Mol File: 257947-27-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: threo-3-phenylisoserineamide(CAS DataBase Reference)
• NIST Chemistry Reference: threo-3-phenylisoserineamide(257947-27-6)
• EPA Substance Registry System: threo-3-phenylisoserineamide(257947-27-6)

Safety Data

• Hazardous Substances Data: 257947-27-6(Hazardous Substances Data)

Upstream product

• 104-55-2 3-phenyl-propenal 
• 17199-29-0 (S)-Mandelic acid 
• 126060-73-9 ethyl (2R,3R)-3-phenyl-2,3-oxiranepropanoate 

Downstream Products

• 257947-28-7 Ethyl (2S,3S) 2-hydroxy-3-amino-3-phenylpropionate Hydrochloride 
• 150949-07-8 methyl (2S,3S)-phenylisoserine 
• 949023-16-9 (4S,5R)-3-benzoyl-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-5-carboxylic acid 
• 32981-85-4 methyl (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanoate 

Relevant articles and documents

A practical and efficient synthesis of taxol C-13 side chain

A practical and efficient synthesis of taxol C-13 side chain from cheap and easily available starting material is described.

Resolution of 2-hydroxy-3-amino-3-phenylpropionamide and its conversion to C-13 sidechain of taxanes

The present invention provides an efficient route to the C-13 side chain of the anti-cancer drug paclitaxel (TAXOL) and its analogs. The process includes the resolution of racemic erythro 2-hydroxy-3-amino-3-phenylpropionamide by diastereomeric crystalliz