258339-27-4Relevant academic research and scientific papers
A new scaffold for dipeptide β-turn mimetics: Expeditious synthesis of an unsaturated 6,5-fused bicyclic lactam
Millet, Regis,Houssin, Raymond,Henichart, Jean-Pierre,Rigo, Benoit
, p. 1279 - 1284 (1999)
Reported here is an easy and short synthesis of 6-acetamido-5-oxo- 1,2,3,5,6,7-hexahydro-3-indolizine-carboxylic acid, originating from β- enaminoesters derived from pyroglutamic acid. This key compound has been used as a scaffold in the synthesis of dipeptido mimetics.
