258339-31-0Relevant academic research and scientific papers
Hexamethyldisilazane in the presence of n,n′,n″n?- tetramethyltetra-2,3-pyridinoporphyrazinato copper (II) is a new, mild and highly efficient reagent for silylation of alcohols and phenols
Akhlaghinia, Batool,Asadi, Mozafar,Safaee, Elham,Heydarpoor, Mozhgan
, p. 2099 - 2104 (2004)
Alcohols and phenols are protected with hexamethyldisilazane in the presence of N,N′,N″,N?-tetramethyletra-2,3- pyridinoporphyrazinato copper (II) in good-to-excellent yields at room temperature.
SURFACE MODIFIED ORGANIC·INORGANIC HYBRID GLASS, PROTECTING GROUP INDUCED ALCOHOL OR ITS DERIVATIVE AND PRODUCING METHOD THEREOF
-
Page/Page column 31-33, (2010/11/28)
Disclosed are a protected alcohol or derivative thereof, a surface- modified organic-inorganic hybrid glass, and preparation methods thereof. More specifically, disclosed are a protected alcohol or derivative thereof and a surface-modified organic-inorganic hybrid glass, which are prepared by allowing a silane compound, having vinyl or a vinyl derivative, to react with an alcohol or derivative thereof or with an organic-inorganic hybrid glass, in the presence of an acid catalyst, a transition metal catalyst and an organic solvent, so as to introduce an organic group thereto even at room temperature, as well as preparation methods thereof. The disclosed invention allows a functional group to be effectively introduced into alcohol or a derivative thereof or into an organic-inorganic hybrid glass, not only high temperatures but also room temperature, and thus is highly effective in introducing compounds having a thermally sensitive functional group, for example, natural compounds or proteins. Also, the invention makes it possible to introduce various organic groups and to separate and purify organic macromolecule-bonded organosilane compounds using a silica gel column so as to effectively introduce large organic functional groups to inorganic materials. Accordingly, the invention is highly useful in the chemical industry.
