258345-13-0Relevant academic research and scientific papers
Synthesis and biological activity of a novel series of indole-derived PPARγ agonists
Henke, Brad R.,Adkison, Kimberley K.,Blanchard, Steven G.,Leesnitzer, Lisa M.,Mook Jr., Robert A.,Plunket, Kelli D.,Ray, John A.,Roberson, Claudia,Unwalla, Rayomand,Willson, Timothy M.
, p. 3329 - 3334 (1999)
The synthesis and structure-activity relationships of a novel series of indole 5-carboxylic acids that bind and activate peroxisome proliferator- activated receptor gamma (PPARγ) are reported. These new analogs are selective for PPARγ vs the other PPAR su
