42205-96-9Relevant academic research and scientific papers
Visible-Light Induced Direct Synthesis of Polysubstituted Furans from Cyclopropyl Ketones
Feng, Liyan,Yan, Hang,Yang, Chao,Chen, Dafa,Xia, Wujiong
, p. 7008 - 7022 (2016/08/30)
In this article, a photoredox protocol for the synthesis of furans via oxidative coupling of olefin generated in situ from cyclopropyl ketones with ketonic oxygen atom is presented. Moreover, bromination of furans in the presence of overstoichiometric oxidant has been achieved with high regioselectivity.
Synthesis and biological activity of a novel series of indole-derived PPARγ agonists
Henke, Brad R.,Adkison, Kimberley K.,Blanchard, Steven G.,Leesnitzer, Lisa M.,Mook Jr., Robert A.,Plunket, Kelli D.,Ray, John A.,Roberson, Claudia,Unwalla, Rayomand,Willson, Timothy M.
, p. 3329 - 3334 (2007/10/03)
The synthesis and structure-activity relationships of a novel series of indole 5-carboxylic acids that bind and activate peroxisome proliferator- activated receptor gamma (PPARγ) are reported. These new analogs are selective for PPARγ vs the other PPAR su
Further Investigations into the Mechanism of the Acid Catalysed Rearrangement of Aryl Substituted Cyclopropyl Ketones
Hantawong, Kesra,Murphy, William S.
, p. 2520 - 2547 (2007/10/02)
The acid catalysed rearrangement of a number of aryl cyclopropyl ketones (2) to tetralones (3) were investigated in situ by 1H and 13C n.m.r. spectroscopy.The formation of oxycyclopentenyl intermediates (4) were observed.The involvement of a concurrent el
