25844-70-6Relevant academic research and scientific papers
Efficient synthesis of substituted 2-aminopyrazines: FeCl3-promoted condensation of hydroxyiminoketones with aminoacetonitriles
Itoh, Takahiro,Maeda, Kenji,Wada, Toshihiro,Tomimoto, Koji,Mase, Toshiaki
, p. 9287 - 9290 (2002)
FeCl3-promoted condensation of hydroxyiminoketones with aminoacetonitriles followed by catalytic hydrogenation afforded the desired pyrazines in moderate-good yields. This protocol provides an efficient and practical synthesis of substituted 2-
