25874-23-1Relevant academic research and scientific papers
β,γ,-UNSATURATED α-AMINO ACID γ-LACTONES; PRECURSORS FOR POLYHYDROXY AMINO ACIDS
Campbell, Malcolm M.,Floyd, Arthur J.,Lewis, Terry,Mahon, Mary F.,Ogilvie, Ronald J.
, p. 1993 - 1996 (1989)
Enantiocomplementary routes to (R)- and (S)-Z-2-amino-5-hydroxy-pent-3-enoic acid lactones are described, starting from D-xylose.
Synthesis of a New Branched Chain Hexopyranosyl Nucleoside: 1--thymine
Augustyns, K.,Rozenski, J.,Aerschot, A. Van,Busson, R.,Claes, P.,Herdewijn, P.
, p. 1189 - 1198 (2007/10/02)
A straightforward synthesis of the branched chain nucleoside 7 is described.This synthesis involves two stereoselective steps: introduction of the hydroxymethyl group on the sugar is achieved by radical cyclization of the (bromomethyl)dimethylsilyl ether of the allylic alcohol 8; the condensation reaction with thymine as base moiety resulted exclusively in the formation of the α-anomer.
