25877-34-3

Usage

Uses

Used in Aerospace and Automotive Industries:
1-Methyl-5-nitro-1H-benzotriazole is used as a corrosion inhibitor for protecting metal surfaces in aerospace and automotive applications. It helps prevent corrosion and degradation, ensuring the longevity and performance of metal components.
Used in Fuel and Lubricants:
1-Methyl-5-nitro-1H-benzotriazole is used as a stabilizer in fuel and lubricants to prevent corrosion and degradation of metal surfaces. Its presence in these products helps maintain the integrity of engines and machinery, reducing the need for frequent maintenance and repairs.
Used in Agricultural and Pharmaceutical Applications:
1-Methyl-5-nitro-1H-benzotriazole has been studied for its potential use as an antifungal agent in agricultural and pharmaceutical applications. Its antifungal properties can be utilized to protect crops from fungal infections and to develop treatments for fungal diseases in humans.
Safety Considerations:

InChI:InChI=1/C7H6N4O2/c1-10-7-3-2-5(11(12)13)4-6(7)8-9-10/h2-4H,1H3

Upstream product

• 2338-12-7 5-nitrobenzotriazole 
• 77-78-1 dimethyl sulfate 
• 41939-61-1 N₁-methyl-4-nitrobenzene-1,2-diamine 
• 74-88-4 methyl iodide 

Downstream Products

• 127280-79-9 1-Methyl-5-nitro-4-(phenylsulfonylmethyl)benzotriazol 
• 127280-80-2 1-Methyl-5-nitro-4-<1-(phenylsulfonyl)propyl>benzotriazol 
• 27799-83-3 1-methyl-1H-benzo [d][1,2,3]triazole-5-amine 

Relevant academic research and scientific papers

Histone lysine methyltransferase NSD2 inhibiting small-molecule compound and application thereof

The invention belongs to the field of chemical medicine and particularly relates to a histone lysine methyltransferase NSD2 inhibiting small-molecule compound. A general formula of the small-moleculecompound is as shown in the specification. According to

HEPARAN SULFATE BIOSYNTHESIS INHIBITORS FOR THE TREATMENT OF DISEASES

Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions in need of inhibition of heparan sulfate biosynthesis.

1H, 13C and 15N NMR spectroscopy and tautomerism of nitrobenzotriazoles

Benzotriazole nitro derivatives were prepared by nitration of the corresponding benzotriazoles and by methylation or cyclization of appropriate nitro-1,2-phenylenediamines. Structures and tautomerism of the nitrobenzotriazoles were studied by multinuclear 1H, 13C, 15N, and 2D NMR spectroscopy and quantum chemistry. Copyright

INHIBITORS OF HISTONE DEACETYLASE

The invention relates to a series of compounds useful for inhibiting histone deacetylase (HDAC) enzymatic activity. The invention also provides a method for inhibiting histone descetylase in a cell using said compounds as well as a method for treating cell proliferative diseases and conditions using said HDAC inhibitors. Further, the invention provides pharmaceutical compositions comprising the HDAC inhibiting compounds and a pharmaceutically acceptable carrier.

Synthesis, antimicrobial data and correlation analysis in a set of 2-alkyl-5-amidobenzotriazoles

A set of 2-alkyl-5-amidobenzotriazoles has been prepared and characterized. Shake-flask partition coefficients (log P) and capacity factors (log k') have been experimentally determined. The in vitro antimicrobial activity against Gram-positive, Gram-negat

THE CHEMISTRY OF N-SUBSTITUTED BENZOTRIAZOLES. PART 18. A STUDY OF THE INFLUENCE OF STRUCTURE ON THE 1- TO 2-(N,N-DIALKYLAMINOALKYL)BENZOTRIAZOLE EQUILIBRIUM

The equilibrium constants, the associated free energies for the equilibria, and the free energies of activation for the isomerization process of a series of 1- and 2-(N,N-dialkylaminoalkyl)benzotriazoles of types (8)-(11) were calculated from the variable temperature 1H-nmr spectra.Trends in the magnitudes of these energies and equilibrium constants are correlated with the molecular structure.