27799-83-3

Basic information

• Product Name: 5-Amino-1-methyl-1H-benzotriazole
• Synonyms: 5-Amino-1-methyl-1H-benzotriazole;1-Methyl-1H-1,2,3-benzotriazol-5-amine;1-Methyl-1H-benzo[d][1,2,3]triazol-5-aMine
• CAS NO: 27799-83-3
• Molecular Formula: C₇H₈N₄
• Molecular Weight: 148.17
• Mol File: 27799-83-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 368.5°Cat760mmHg
• Flash Point: 176.7°C
• Appearance: /
• Density: 1.42g/cm³
• Vapor Pressure: 1.27E-05mmHg at 25°C
• Refractive Index: 1.727
• PKA: 3.01±0.50(Predicted)
• CAS DataBase Reference: 5-Amino-1-methyl-1H-benzotriazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Amino-1-methyl-1H-benzotriazole(27799-83-3)
• EPA Substance Registry System: 5-Amino-1-methyl-1H-benzotriazole(27799-83-3)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 27799-83-3(Hazardous Substances Data)

Usage

General Description

5-Amino-1-methyl-1H-benzotriazole is a specialized organic compound that is part of the benzotriazole chemical family. Chemical formulas for this compound include C8H9N3 and CAS number 16011-69-1. As a niche compound, it is not widely used but has relevance in specific scientific research and industrial contexts. This chemical is characterized by its notable features including a white crystalline powder appearance and its solubility in various solvents. As with many chemicals, it should be handled with care due to potential risks and hazards associated with its use, and stored following regulatory guidelines to ensure safety.

InChI:InChI=1/C7H8N4/c1-11-7-3-2-5(8)4-6(7)9-10-11/h2-4H,8H2,1H3

Upstream product

• 944718-31-4 5-bromo-1-methyl-1H-benzo[d][1,2,3]triazole 
• 41939-61-1 N₁-methyl-4-nitrobenzene-1,2-diamine 
• 2338-12-7 5-nitrobenzotriazole 
• 25877-34-3 1-methyl-5-nitro-1H-benzo[d][1,2,3]triazole 

Relevant articles and documents

Histone lysine methyltransferase NSD2 inhibiting small-molecule compound and application thereof

The invention belongs to the field of chemical medicine and particularly relates to a histone lysine methyltransferase NSD2 inhibiting small-molecule compound. A general formula of the small-moleculecompound is as shown in the specification. According to

Substituted heteroaryl compounds and compositions and uses thereof (by machine translation)

The invention discloses substituted heteroaryl compounds and compositions thereof and their use. The compounds of formula (I) compound or type shown in (I) a compound represented by stereo isomers, tautomers, nitrogen oxide, solvate, metabolite, pharmaceutically acceptable salt or its prodrug. The invention also provides a pharmaceutical composition, the compounds and pharmaceutical compositions can be regulated protein kinase, particularly Aurora kinase and JAK kinase activity, for the prevention, treatment, treatment and reduce protein kinase, in particular JAK kinase activity mediated diseases or disorders. (by machine translation)

INHIBITORS OF HISTONE DEACETYLASE

The invention relates to a series of compounds useful for inhibiting histone deacetylase (HDAC) enzymatic activity. The invention also provides a method for inhibiting histone descetylase in a cell using said compounds as well as a method for treating cell proliferative diseases and conditions using said HDAC inhibitors. Further, the invention provides pharmaceutical compositions comprising the HDAC inhibiting compounds and a pharmaceutically acceptable carrier.