258826-31-2

Upstream product

• 76-83-5 trityl chloride 
• 1095-85-8 2-amino tritylthio ethane 
• 79-04-9 chloroacetyl chloride 
• 76-84-6 triphenylmethyl alcohol 
• 15297-43-5 <2-<(triphenylmethyl)thio>ethyl>amine hydrochloride 

Downstream Products

• 152863-83-7 N-[2-[(triphenylmethyl)thio]ethyl]-2-[[2-[(triphenylmethyl)thio]ethyl]amino]acetamide 
• 459839-45-3 N-[2-((triphenylmethyl)thio)ethyl]-3-aza-3-[2-((triphenylmethyl)thio)ethyl]heptadecanamide 
• 1539311-26-6 trimethyl-γ-L-glutamyl-L-glutamyl-7,10-diaza-9-oxo-7-[2-(triphenylmethyl)thioethyl]-12-[(triphenylmethyl)-thio]dodecanamide 
• 228253-37-0 methyl 7,10-diaza-9-oxo-7-[2-((triphenylmethyl)thio)-ethyl]-12-[(triphenylmethyl)thio]dodecanoate 
• 1353721-33-1 (6-[3',6'-diaza-5'-oxo-3'-(2-triphenylmethylthioethyl)-8'-triphenylmethylthio]octanamidohexyl β-N-acetylgalactoseamine per-o-acetate) 
• 1353721-35-3 (6-[3',6'-diaza-5'-oxo-3'-(2-triphenylmethyl thioethyl)-8'-triphenylmethylthio]octanamidohexyl β-N-acetylgalactosamine) 
• 228253-42-7 3,6-diaza-5-oxo-3-[2-((triphenylmethyl)thio)ethyl]-8-[(triphenylmethyl)thio]octanoic acid 
• 258826-26-5 3,5-dimethyl-4-{(2-tritylsulfanyl-ethyl)-[(2-tritylsulfanyl-ethylcarbamoyl)-methyl]-carbamoyl}-1H-pyrrole-2-carboxylic acid benzyl ester 
• 258826-33-4 heptanoic acid (2-tritylsulfanyl-ethyl)-[(2-tritylsulfanyl-ethylcarbamoyl)-methyl]-amide 
• 258826-34-5 2-[hexyl-(2-tritylsulfanyl-ethyl)-amino]-N-(2-tritylsulfanyl-ethyl)-acetamide 

Relevant academic research and scientific papers

Compounds with double-functional group and method of manufacturing the same

The invention relates to a compounds with double-functional group and method of manufacturing the same, its chemical structure is provided with two main functional group, the two nitrogen-sulfur mix-seat, radioactive isotope combination with; its two-for

Bifunctional compound and method for manufacturing the same

A bifunctional compound and a method for manufacturing the same are revealed. The structural formula of the compound includes two main functional groups. One functional group is a diamide dithiolate (N2S2) ligand able to bind with radioisotopes. The other functional group is polybasic carboxylic acid that binds to biochemical substances. Based on properties of the above two functional groups, the compound of the present invention can be used for preparation of radiopharmaceuticals such as radiotracter for disease diagnosis or radioactive therapeutic agent for disease treatment.

PRECURSOR USED FOR LABELING HEPATORCYTE RECEPTOR AND CONTAINING TRISACCHARIDE AND DIAMIDE DEMERCAPTIDE LIGAND, METHOD FOR PREPARING THE SAME, RADIOTRACER AND PHARMACEUTICAL COMPOSITION OF THE SAME

A precursor used for labeling hepatocyte receptors and applied to radiotracers for imaging or pharmaceutical compositions for liver cancers is revealed. The precursor is a bifunctional compound. The bifunctional group includes a trisaccharide structure an

BIFUNCTIONAL COMPOUND WITH MONOSACCHARIDE AND N2S2 LIGAND, AND PREPARATION AND USE THEREOF

A bifunctional compound with a monosaccharide and a N2S2 ligand, and more particularly, a bifunctional compound with a N2S2 ligand and aminohexylacetyl galactosamine (ah-GalNAc4) is provided. A method for preparing the bifunctional compound with a monosaccharide and a N2S2 ligand is also provided, including activating a carboxyl group in an organic ligand, reacting the activated carboxyl group with a galactopyranoside through amidation, and then hydrolyzing. The bifunctional compound of the present invention is widely useful in nuclear medicine for preparation of liver imaging agents for assisting in correct diagnosis of diseases.

H3LMN COMPOUND USED AS RADIOACTIVE AGENT FOR TREATMENT OF LIVER CANCER AND MANUFACTURING METHOD THEREOF

H3LMN series compounds used as radioactive agents for treatment of liver cancer and a manufacturing method thereof are revealed. 2-thioethylamine hydrochloride is reacted with triphenylmethanol for protection of thiol to obtain 2-[(triphenylmet

Compound containing carboxylate ester and N2S2 ligand bi-functional groups and manufacturing method thereof

A compound containing carboxylate ester and N2S2 ligand bi-functional groups and a manufacturing method thereof are disclosed. The S in the N2S2 ligand of the compound containing carboxylate ester and N2S2 ligand bi-functional groups includes a protective

Compound containing carboxylate ester and N2S2 ligand bi-functional groups and manufacturing method thereof

A compound containing carboxylate ester and N2S2 ligand bi-functional groups and a manufacturing method thereof are disclosed. The S in the N2S2 ligand of the compound containing carboxylate ester and N2S2 ligand bi-functional groups includes a protective

Efficient method for the synthesis of bisaminoethanethiols and their pyrrole conjugates

By following the protection and deprotection approach, an efficient method for the preparation of bisaminoethanethiol ligands (N2S2) is discussed. In our attempts to synthesize certain nonpeptide analogs of neurotensin, moldel studies were performed by using these ligands for preparing the corresponding pyrrole based conjugates. This methodology provides an alternate approach for developing various target specific agents that cross the blood brain barrier.