258850-20-3

Basic information

• Product Name: (+/-)-methyl 2-[[(2-amino-5-chlorophenyl)methyl]amino]-3-methylbutanoate
• Synonyms: (+/-)-methyl 2-[[(2-amino-5-chlorophenyl)methyl]amino]-3-methylbutanoate
• CAS NO: 258850-20-3
• Molecular Weight: 270.759
• Mol File: 258850-20-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+/-)-methyl 2-[[(2-amino-5-chlorophenyl)methyl]amino]-3-methylbutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-methyl 2-[[(2-amino-5-chlorophenyl)methyl]amino]-3-methylbutanoate(258850-20-3)
• EPA Substance Registry System: (+/-)-methyl 2-[[(2-amino-5-chlorophenyl)methyl]amino]-3-methylbutanoate(258850-20-3)

Safety Data

• Hazardous Substances Data: 258850-20-3(Hazardous Substances Data)

Upstream product

• 258850-15-6 (+/-)-methyl 2-[[(5-chloro-2-nitrophenyl)methyl]amino]-3-methylbutanoate 
• 73033-58-6 5-chloro-2-nitrobenzyl alcohol 
• 5619-05-6 DL-valine methyl ester hydrochloride 
• 209688-13-1 5-chloro-2-nitrobenzyl methanesulfonate 

Downstream Products

• 258850-11-2 7-chloro-3-isopropyl-1,3,4,5-tetrahydro-benzo[e][1,4]diazepin-2-one 
• 258850-00-9 7-chloro-3-isopropyl-2-thioxo-1,2,3,5-tetrahydro-benzo[e][1,4]diazepine-4-carboxylic acid tert-butyl ester 
• 258850-03-2 7-chloro-3-isopropyl-1-methyl-2-oxo-1,2,3,5-tetrahydro-benzo[e][1,4]diazepine-4-carboxylic acid tert-butyl ester 
• 258849-99-9 7-chloro-3-isopropyl-2-oxo-1,2,3,5-tetrahydro-benzo[e][1,4]diazepine-4-carboxylic acid tert-butyl ester 
• 258849-96-6 7-chloro-3-isopropyl-4-(3-methyl-but-2-enyl)-1,3,4,5-tetrahydro-benzo[e][1,4]diazepin-2-one 

Relevant articles and documents

Synthesis and anti-HIV activity of 1,3,4,5-tetrahydro-2H-1,4- benzodiazepin-2-one (TBO) derivatives. Truncated 4,5,6,7-tetrahydro-5- methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-ones (TIBO) analogues

4,5,6,7-Tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)- ones (TIBO), 1, have been shown to significantly inhibit HIV-1 replication, as reported in detail in our prior publications. Since our earlier reports, we have modified the TIBO structu