25894-46-6

Upstream product

• 67-56-1 methanol 
• 17649-87-5 3-methyl-4,4-bis(methylthio)but-3-en-2-one 
• 400723-23-1 9,9-bis(methylthio)-8-methyl-1-phenyl-2,4,6,8-nonatetraene-1-one 
• 100-52-7 benzaldehyde 
• 129611-83-2 7,7-bis(methylthio)-6-methyl-2,4,6-heptatrienal 
• 129611-81-0 5,5-bis(methylthio)-4-methyl-2,4-pentadienal 
• 15081-13-7 3-methyl-4,4-bis-methylsulfanyl-but-3-en-2-ol 
• 13466-40-5 (2E, 4E)-5-phenylpenta-2,4-dienal 
• 103815-47-0 4-(diethoxyphosphoryl)-2-methylbut-2-enoic acid methyl ester 

Downstream Products

• 25279-33-8 6-Methyl-13-phenyltrideca-4,6,8,10,12-pentaen-3-on 
• 25894-52-4 2-Methyl-9-phenylnonatetra-2,4,6,8-en-1-al 
• 25894-49-9 2-Methyl-9-phenylnonatetra-2,4,6,8-en-1-ol 

Relevant academic research and scientific papers

A new 1,5- to 1,11-carbonyl transposition protocol involving ketene dithioacetal chemistry: An efficient polyene synthesis

An efficient strategy for alternative 1,5-, 1,7-, 1,9- and 1,11- carbonyl transposition has been developed via 1,2-reductive or alkylative addition to 5,5-bis(methylthio)-2,4-pentadienals 3a-b, 7,7-bis(methylthio)-2,4,6-heptatrienones 5,9,9-bis(methylthio)-2,4,6,8-nonatetraenones 8 and 11,11-bis(methylthio)-2,4,6,8,10-undecapentaenones 11 followed by BF3,Et2O induced methanolysis of the resulting carbinols to the corresponding polyene esters. The synthesis of the novel polyene aldehydes 3a-b, 7a-b, 10b and polyenones 5, 8, 11 precursors has also been described following iterative Vielsmeier-Haack reaction and aldol condensation.