25906-63-2

Upstream product

• 123-31-9 hydroquinone 
• 610-92-4 2,5-dihydroxy-1,4-benzenedicarboxylic acid 
• 5870-38-2 diethyl 2,5-(dihydroxy)terephthalate 
• 16420-13-6 N,N-Dimethylthiocarbamoyl chloride 

Downstream Products

• 25906-67-6 2,5-bis(dimethylthiocarbamoylsulfanyl)terephthalic acid diethyl ester 
• 25902-98-1 2,5-bis(dimethylthiocarbamoylsulfanyl)terephthalic acid diethyl ester 
• 154822-13-6 2,5-Dimercapto-1,4-phenylendimethanol 
• 25906-66-5 2,5-disulfhydrylbenzene-1,4-dicarboxylic acid 
• 1227-49-2 3,3'-dithiobis-benzoic acid 

Relevant academic research and scientific papers

Cation-exchanged conductive Mn2DSBDC metal–organic frameworks: Synthesis, structure, and THz conductivity

Conductive metal–organic frameworks (MOFs) are an emerging class of materials that rely upon crystallographically-defined charge-transport pathways that can be synthetically designed. Such conductive MOFs, including Mn-based MOFs, have not yet found applications in electrocatalysis at least partly due to restrictions in their tunability, as compositional or structural changes may interrupt the purposefully-designed charge-transport pathways. In this work, we provide an original strategy to exchange a portion of the Mn2+ cations in the conductive MOF Mn2DSBDC (where DSBDC = 2,5-dimercaptoterephthalate) for either Ni2+, Cu2+, or Co2+. The bulk and local structures were characterized using powder X-ray diffraction and element-specific X-ray absorption spectroscopy, respectively, to understand the structural effects of cation exchange, supporting that cation exchange does not alter the overall structure of the MOF. Importantly, using time-domain THz spectroscopy, it was discovered that the cation exchange does not alter the conductivity of the MOF. This finding opens the door to functionalization and tunability with respect to the cation composition in Mn2DSBDC, strongly suggesting applications in electrocatalysis.

Mn2(2,5-disulfhydrylbenzene-1,4-dicarboxylate): A microporous metal-organic framework with infinite (-Mn-S-)∞ chains and high intrinsic charge mobility

The reaction of MnCl2 with 2,5-disulfhydrylbenzene-1,4- dicarboxylic acid (H4DSBDC), in which the phenol groups in 2,5-dihydroxybenzene-1,4-dicarboxylic acid (H4DOBDC) have been replaced by thiophenol units, led to the isolation of Mn2(DSBDC), a thiolated analogue of the M2(DOBDC) series of metal-organic frameworks (MOFs). The sulfur atoms participate in infinite one-dimensional Mn-S chains, and Mn2(DSBDC) shows a high surface area and high charge mobility similar to that found in some of the most common organic semiconductors. The synthetic approach to Mn2(DSBDC) and its excellent electronic properties provide a blueprint for a potentially rich area of exploration in microporous conductive MOFs with low-dimensional charge transport pathways.

Glutathione-responsive nanoscale MOFs for effective intracellular delivery of the anticancer drug 6-mercaptopurine

A glutathione-triggered drug delivery system (DDS) based on nanoscale metal-organic frameworks (NMOFs) is developed, which features an intracellular redox-responsive release of an anticancer drug. Compared to normal cells, the current NMOF-based DDS has 3-fold higher cytotoxicity to cancer cells, prefiguring its great potential for selective cancer therapy.

A mercapto-functionalized MOFs material and its preparation and to absorb and remove the application of heavy metal ions in the water body

The invention relates to a preparation method for a thiol-functionalization MOFs material and application thereof in adsorption and removal of heavy metal ions in water. The thiol-functionalization MOFs (UiO-66-SH) material can effectively adsorb and remo

On-Demand Cyclophanes: Substituent-Directed Self-Assembling, Folding, and Binding

A family of p-cyclophanes based on bis- or tetrafunctionalized 1,4-bisthiophenol units linked by disulfide bridges was obtained by self-assembly on a gram scale and without any chromatographic purification. The nature of the functionalities borne by these so-called dyn[4]arenes plays a crucial role on their structural features as well as their molecular recognition abilities. Tuning these functions on demand yields tailored receptors for cations, anions, or zwitterions in organic or aqueous media.

Zirconium-based sulfonic metal-organic framework and its manufauring process

The present invention relates to a sulfonic acid group-induced zirconium-based metal-organic framework and a manufacturing method thereof. The sulfonic acid group-induced zirconium-based metal-organic framework is represented by chemical formula 1, [Zr_6O_4(OH)_4(C_8H_4O_10S_2)_6]m, has excellent proton conductivity, and exhibits long-term stability with respect to the proton conductivity.(AA) Chemical formula 4(BB) Chemical formula 5(CC) Chemical formula 7COPYRIGHT KIPO 2016

Controlling the biological effects of spermine using a synthetic receptor

Polyamines play an important role in biology, yet their exact function in many processes is poorly understood. Artificial host molecules capable of sequestering polyamines could be useful tools for studying their cellular function. However, designing synthetic receptors with affinities sufficient to compete with biological polyamine receptors remains a huge challenge. Binding affinities of synthetic hosts are typically separated by a gap of several orders of magnitude from those of biomolecules. We now report that a dynamic combinatorial selection approach can deliver a synthetic receptor that bridges this gap. The selected receptor binds spermine with a dissociation constant of 22 nM, sufficient to remove it from its natural host DNA and reverse some of the biological effects of spermine on the nucleic acid. In low concentrations, spermine induces the formation of left-handed DNA, but upon addition of our receptor, the DNA reverts back to its right-handed form. NMR studies and computer simulations suggest that the spermine complex has the form of a pseudo-rotaxane. The spermine receptor is a promising lead for the development of therapeutics or molecular probes for elucidating spermine's role in cell biology.