5870-38-2Relevant articles and documents
Amorphous Pure Organic Polymers for Heavy-Atom-Free Efficient Room-Temperature Phosphorescence Emission
Ma, Xiang,Xu, Chao,Wang, Jie,Tian, He
, p. 10854 - 10858 (2018)
Pure organic, heavy-atom-free room-temperature phosphorescence (RTP) materials have attracted much attention and have potential applications in photoelectric and biochemical material fields owing to their rich excited state properties. They offer long luminescent lifetime, diversified design, and facile preparation. However, recent achievements of efficient phosphorescence under ambient conditions mainly focus on ordered crystal lattices or embedding into rigid matrices, which require strict growth conditions and have poor reproducibility. Herein, we developed a concise approach to give RTP with a decent quantum yield and ultralong phosphorescence lifetime in the amorphous state by radical binary copolymerization of acrylamide and different phosphors with oxygen-containing functional groups. The cross-linked hydrogen-bonding networks between the polymeric chains immobilize phosphors to suppress non-radiative transitions and provide a microenvironment to shield quenchers.
Discovery of novel 2,5-dihydroxyterephthalamide derivatives as multifunctional agents for the treatment of Alzheimer's disease
Song, Qing,Li, Yan,Cao, Zhongcheng,Liu, Hongyan,Tian, Chaoquan,Yang, Ziyi,Qiang, Xiaoming,Tan, Zhenghuai,Deng, Yong
, p. 6115 - 6127 (2018)
A series of 2,5-dihydroxyterephthalamide derivatives were designed, synthesized and evaluated as multifunctional agents for the treatment of Alzheimer's disease. In vitro assays demonstrated that most of the derivatives exhibited good multifunctional activities. Among them, compound 9d showed the best inhibitory activity against both RatAChE and EeAChE (IC50 = 0.56 μM and 5.12 μM, respectively). Moreover, 9d exhibited excellent inhibitory effects on self-induced Aβ1–42 aggregation (IC50 = 3.05 μM) and Cu2+-induced Aβ1–42 aggregation (71.7% at 25.0 μM), and displayed significant disaggregation ability to self- and Cu2+-induced Aβ1–42 aggregation fibrils (75.2% and 77.2% at 25.0 μM, respectively). Furthermore, 9d also showed biometal chelating abilities, antioxidant activity, anti-neuroinflammatory activities and appropriate BBB permeability. These multifunctional properties highlight 9d as promising candidate for further studies directed to the development of novel drugs against AD.
Robust covalent organic frameworks with tailor-made chelating sites for synergistic capture of U(vi) ions from highly acidic radioactive waste
Yu, Jipan,Lan, Jianhui,Wang, Shuai,Zhang, Pengcheng,Liu, Kang,Yuan, Liyong,Chai, Zhifang,Shi, Weiqun
supporting information, p. 3792 - 3796 (2021/03/29)
A synergistic strategy for enhancing U(vi) capture under highly acidic conditions (2 M HNO3) by radiation resistant phosphonate-functionalized two-dimensional covalent organic frameworks with tailor-made binding sites bearing a strong affinity was described. The combination of the radiation resistant characteristic with a strong acid-resistant property endows COFs with practical capabilities for actinide capture from real radioactive liquid waste.
Crystal Flexibility Design through Local and Global Motility Cooperation
Wang, Ping,Otake, Ken-ichi,Hosono, Nobuhiko,Kitagawa, Susumu
supporting information, p. 7030 - 7035 (2021/02/26)
Incorporating local mobility into a flexible framework promises to create cooperative properties unattainable in a conventional soft porous crystal. In this study, we propose a design strategy that integrates substituent moieties and a flexible porous crystal framework via intra-framework π–π interactions. This integration not only facilitates framework structural transitions but also gives the porous coordination polymers (PCPs) different guest-free structures that depend on the activation conditions. The incorporated flexibility gives the material the ability to discriminate C6 alkane isomers based on different gate-opening behaviors. Thus, the PCP has potential applications in C6 isomer separation, a critical step in the petroleum refining process to produce gasoline with high octane rating. This strategy, based on ligand designability, offers a new approach to flexible PCP structural and functional design.
A Single-Benzene-Based Fluorophore: Optical Waveguiding in the Crystal Form
Cho, Eunbee,Choi, Jinho,Jo, Seonyoung,Park, Dong-Hyuk,Hong, Young Ki,Kim, Dongwook,Lee, Taek Seung
, p. 1130 - 1134 (2019/09/06)
A single-benzene-based, blue-emissive diethyl 2,5-dihydroxyterephthalate (DDT) was prepared by Fischer esterification of 2,5-dihydroxyterephthalic acid (DHT) and ethanol. The strong fluorescence in both the solution and the solid state from such a simple framework stemmed from the push-pull structure of the electron-donating hydroxy groups and the accepting carbonyl groups, as well as structural planarity from intramolecular hydrogen bonds. The strong intermolecular hydrogen bonds enabled DDT to crystallize easily. The color CCD imaging technique showed efficient 1D optical waveguiding with a large optical loss coefficient of 0.15 dB/μm. DDT has potential application in optical sensors, photonic devices, and optoelectronic communication, because of its highly ordered structure and light-emitting ability.
