259088-63-6Relevant articles and documents
Improved synthesis of the bifunctional chelating agent 1,4,7,10- tetraaza-N-(1-carboxy-3-(4-nitrophenyl)propyl)-N',N'',N'''-tris(acetic acid)cyclododecane (PA-DOTA)
Chappell, Lara L.,Rogers, Buck E.,Khazaeli,Mayo, Matthew S.,Buchsbaum, Donald J.,Brechbiel, Martin W.
, p. 2313 - 2320 (1999)
A concise synthesis of the bifunctional chelating agent 1,4,7,10- tetraaza-N-(1-carboxy-3-(4-nitrophenyl)propyl)-N','',N'''-tris(acetic acid)cyclododecane (PA-DOTA) is reported. Difficulties involving the production of partially alkylated products and the