259185-89-2

Upstream product

• 67-56-1 methanol 

Downstream Products

• 259185-91-6 N-allyl-N-(2-tert-butyl-phenyl)-2-oxo-butyramide 
• 259185-92-7 N-allyl-N-(2-tert-butyl-phenyl)-2-oxo-3-phenyl-propionamide 
• 259185-93-8 (R)-N-allyl-N-2-(tert-butyl)phenyl 2-oxo-2-phenylacetamide 
• 259185-98-3 2-allyl-2-hydroxy-pent-4-enoic acid (2-tert-butyl-phenyl)-propyl-amide 
• 205237-66-7 N-allyl-N-(2-tert-butyl-phenyl)-2-hydroxy-propionamide 
• 193410-54-7 N-acryl-N-allyl-2-tert-butylanilide 
• 259185-90-5 N-allyl-N-(2-tert-butyl-phenyl)-2-oxo-propionamide 

Relevant academic research and scientific papers

Efficient synthesis of various atropisomeric amides in optically pure forms and their application to asymmetric reactions

Various atropisomeric amides were prepared in optically pure forms (≥98% ee) through the optical resolution of the amide ester derived from (R)-pantolactone, N-allyl-ortho-tert-butylaniline and oxalyl chloride. Asymmetric carbonyl addition reaction of an alkyllithium and asymmetric iodolactonization with these atropisomeric amides proceeded with high stereoselectivity.