2592-86-1

Basic information

• Product Name: Lithium, (3-bromophenyl)-
• CAS NO: 2592-86-1
• Molecular Formula: C6H4BrLi
• Molecular Weight: 162.943
• Mol File: 2592-86-1.mol

Chemical Properties

• CAS DataBase Reference: Lithium, (3-bromophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Lithium, (3-bromophenyl)-(2592-86-1)
• EPA Substance Registry System: Lithium, (3-bromophenyl)-(2592-86-1)

Safety Data

• Hazardous Substances Data: 2592-86-1(Hazardous Substances Data)

Upstream product

• 108-36-1 1,3-dibromobenzene 
• 80-10-4 diphenylsilyl dichloride 
• 109-72-8 n-butyllithium 

Downstream Products

• 1000201-09-1 [3-(3-bromo-phenyl)-3-(4-hydroxy-phenyl)-3H-isoindol-1-yl]-carbamic acid tert-butyl ester 
• 1000201-10-4 {3-(3-bromo-phenyl)-3-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-3H-isoindol-1-yl}-carbamic acid tert-butyl ester 
• 1000201-08-0 methanesulfonic acid 4-[1-(3-bromo-phenyl)-3-tert-butoxycarbonylamino-1H-isoindol-1-yl]-phenyl ester 
• 1421009-56-4 (3-bromophenyl)(dibenzo[b,d]thiophen-4-yl)diphenylsilane 
• 132318-10-6 3-[2]quinolyl-benzoic acid 
• 75307-71-0 4,6-Bis(3-bromphenyl)pyrimidin 
• 75307-74-3 3,3'-Bis<6-(3-chlorphenyl)-4-pyrimidinyl>biphenyl 
• 75307-73-2 3-<6-(3-Chlorphenyl)-4-pyrimidinyl>-3'-(6-phenyl-4-pyrimidinyl)biphenyl 
• 75307-72-1 4,6-Bis(3-lithiophenyl)pyrimidin 
• 75307-75-4 1,3-Di(4-pyrimidinyl)benzol 
• 3977-48-8 4,6-diphenylpyrimidine 
• 137103-58-3 1-(4-Fluoro-phenyl)-2-imidazol-1-yl-1-(3-pyridin-3-yl-phenyl)-ethanol 
• 137103-57-2 1-(4-Fluoro-phenyl)-2-imidazol-1-yl-1-(3-pyridin-2-yl-phenyl)-ethanol 
• 137103-59-4 1-(4-fluorophenyl)-1-[3-(pyridin-4-yl)phenyl]-2-(1-imidazolyl)ethanol 

Relevant articles and documents

TRIPHENYLENE SILANE HOSTS

Novel aryl silicon and aryl germanium host materials, and in particular host materials containing triphenylene and pyrene fragments, are described. These compounds improve OLED device performance when used as hosts in the emissive layer of the OLED.

New Compounds 319

This invention relates to novel compounds having the structural formula I below: and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.

SUBSTITUTED ISOINDOLES AS BACE INHIBITORS AND THEIR USE

This invention relates to novel compounds having the structural formula I and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.

Preliminary Studies of the Mechanism of Metal-Halogen Exchange. The Kinetics of Reaction of n-Butyllithium with Substituted Bromobenzenes in Hexane Solution

Initial measurements of the rate of reaction of bromobenzene with n-butyllithium in hexane solution have shown the exchange to be first order in bromobenzene and first order in n-butyllithium, with an activation energy of 12 kcal mol-1 (52 kJ mol-1).A Hammett relationship for the reaction of substituted bromobenzenes with n-butyllithium suggests negative charge character in the transition state (ρ ca 2).The addition of a Lewis donor (p-methylanisole) to the hexane solution was found to result in an increase in the rate of exchange, but did not affect the Hammett reaction constant.Several transition-state structures are considered; available evidence suggests that the exchange may be concerted, with either a four-centered structure, or SN2-type attack of the n-butyl anion at the bromine of the aryl bromide

Heterocyclopolyaromatics, IX: 4,4''',6,6'''-Tetraazahexa-m-phenylene and 4,4',4''',4'''',6,6',6''',6''''-Octaazahexa-m-phenylene

The synthesis of the title compounds 4 and 9 is described.In contrast to hexa-m-phenylene (6) 4,4''',6,6'''-tetrazahexa-m-phenylene (4) is planar.This is explained by less Pitzer strain in the outer sphere of 4.From 4 a tetranitro derivative (7c) was obta