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Pyrimidine, 4,6-diphenyl-, also known as 4,6-diphenylpyrimidine, is an organic compound with the chemical formula C14H10N2. It is a derivative of the pyrimidine heterocyclic ring system, which consists of a six-membered aromatic ring containing four carbon atoms and two nitrogen atoms. The diphenyl substitution refers to the presence of two phenyl groups (C6H5) attached to the 4 and 6 positions of the pyrimidine ring. Pyrimidine, 4,6-diphenyl- is of interest in organic chemistry and medicinal chemistry due to its potential applications in the synthesis of various pharmaceuticals and agrochemicals. It can be used as a building block for the development of new compounds with specific biological activities, such as antiviral, anticancer, and antimicrobial properties. The synthesis of 4,6-diphenylpyrimidine can be achieved through various methods, including condensation reactions and cyclization processes, and its properties can be further modified by introducing additional functional groups or substituents.

3977-48-8

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3977-48-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3977-48-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,9,7 and 7 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 3977-48:
(6*3)+(5*9)+(4*7)+(3*7)+(2*4)+(1*8)=128
128 % 10 = 8
So 3977-48-8 is a valid CAS Registry Number.

3977-48-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4,6-diphenylpyrimidine

1.2 Other means of identification

Product number -
Other names 4,6-diphenyl-pyrimidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3977-48-8 SDS

3977-48-8Relevant academic research and scientific papers

A C4N4 Diaminopyrimidine Fluorophore

Noda, Hidetoshi,Asada, Yasuko,Maruyama, Tatsuro,Takizawa, Naoki,Noda, Nobuo N.,Shibasaki, Masakatsu,Kumagai, Naoya

, p. 4299 - 4304 (2019)

A new scaffold for producing efficient organic fluorescent materials was identified: 2,5-diamino-4,6-diarylpyrimidine featuring a C4N4 elemental composition. Single-step installation of two aryl groups at the 4,6-positions of the pyrimidine core delivered

Highly luminescent dinuclear platinum(II) complexes incorporating bis-cyclometallating pyrazine-based ligands: A versatile approach to efficient red phosphors

Culham, Stacey,Lanoe, Pierre-Henri,Whittle, Victoria L.,Durrant, Marcus C.,Williams, J. A. Gareth,Kozhevnikov, Valery N.

, p. 10992 - 11003 (2013)

A series of luminescent dinuclear platinum(II) complexes incorporating diphenylpyrazine-based bridging ligands (LnH2) has been prepared. Both 2,5-diphenylpyrazine (L2H2) and 2,3-diphenylpyrazine (L3H2) are able to undergo cyclometalation of the two phenyl rings, with each metal ion binding to the two nitrogen atoms of the central heterocycle, giving, after treatment with the anion of dipivaloyl methane (dpm), complexes of formula {Pt(dpm)} 2Ln. These compounds are isomers of the analogous complex of 4,6-diphenylpyrimidine (L1H2). Related complexes of dibenzo(f,h)quinoxaline (L4H2), 2,3-diphenyl-quinoxaline (L5H2), and dibenzo[3,2-a:2′,3′-c]phenazine (L6H2) have also been prepared, allowing the effects of strapping together the phenyl rings (L4H2 and L 6H2) and/or extension of the conjugation from pyrazine to quinoxaline (L5H2 and L6H2) to be investigated. In all cases, the corresponding mononuclear complexes, Pt(dpm)LnH, have been isolated too. All 12 complexes are phosphorescent in solution at ambient temperature. Emission spectra of the dinuclear complexes are consistently red shifted compared to their mononuclear analogues, as are the lowest energy absorption bands. Electrochemical data and TD-DFT calculations suggest that this effect arises primarily from stabilization of the LUMO. Introduction of the second metal ion also has the effect of substantially increasing the molar absorptivity and, in most cases, the radiative rate constants. Meanwhile, extension of conjugation in the heterocycle of L5H2 and L6H2 and planarization of the aromatic system favored by interannular bond formation in L 4H2 and L6H2 leads to further red shifts of the absorption and emission spectra to wavelengths that are unusually long for cyclometalated platinum(II) complexes. The results may offer a versatile design strategy for tuning and optimizing the optical properties of d-block metal complexes for contemporary applications.

Highly efficient orange phosphorescent organic light-emitting diodes based on an iridium(III) complex with diethyldithiocarbamate (S^S) as the ancillary ligand

Mei, Qunbo,Chen, Chen,Tian, Ruqiang,Yang, Min,Tong, Bihai,Hua, Qingfang,Shi, Yujie,Fan, Quli,Ye, Shanghui

, p. 64003 - 64008 (2016)

A novel iridium(iii) complex Ir(dpp)2(dta) (dppH = 4,6-diphenyl pyrimidine; dta = diethyldithiocarbamate) was synthesized and characterized. The complex displayed strong emissions at 575 nm with high photoluminescence quantum yields of 86% in the doped poly(methyl methacrylate) (PMMA) film at 1% doping concentration. The orange-yellow polymer light-emitting devices (PLEDs) based on Ir(dpp)2(dta) as a triplet emitter with different concentrations (x = 1%, 3%, 5%, 7% and 10%) doped in a polymeric host 70% poly(N-vinylcarbazole) (PVK) + 30% 2,2′-(1,3-phenylene)bis[5-(4-tert-butylphenyl)-1,3,4-oxadiazole] (OXD-7) were fabricated with high luminance and efficiency. The device achieved an ideal turn-on voltage (-2) as well as electroluminescence efficiency (30.12 cd A-1) at 3% doping concentration.

Iron-Catalyzed Alkyne-Based Multicomponent Synthesis of Pyrimidines under Air

Chakraborty, Gargi,Guin, Amit Kumar,Mondal, Rakesh,Paul, Nanda D.,Sarkar, Susmita

, p. 13186 - 13197 (2021/10/01)

An iron-catalyzed sustainable, economically affordable, and eco-friendly synthetic protocol for the construction of various trisubstituted pyrimidines is described. A wide range of trisubstituted pyrimidines were prepared using a well-defined, easy to prepare, bench-stable, and phosphine-free iron catalyst featuring a redox-noninnocent tridentate arylazo pincer under comparatively mild aerobic conditions via dehydrogenative functionalization of alcohols with alkynes and amidines.

Synthesis and biological evaluation of pyrimidine bridged combretastatin derivatives as potential anticancer agents and mechanistic studies

Kumar, Bhupinder,Sharma, Praveen,Gupta, Vivek Prakash,Khullar, Madhu,Singh, Sandeep,Dogra, Nilambra,Kumar, Vinod

, p. 130 - 140 (2018/03/23)

A number of pyrimidine bridged combretastatin derivatives were designed, synthesized and evaluated for anticancer activities against breast cancer (MCF-7) and lung cancer (A549) cell lines using MTT assays. Most of the synthesized compounds displayed good

Heterocyclic compound

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Page/Page column 116; 117; 118, (2016/10/07)

Provided is a novel heterocyclic compound which can be used for a light-emitting element, as a host material of a light-emitting layer in which a light-emittiing substance is dispersed. A heterocyclic compound represented by a general formula (G1) is prov

Composite material, light-emitting element, light-emitting device, electronic device, and lighting device

-

Page/Page column 95-96, (2016/08/10)

A composite material which includes an organic compound and an inorganic compound and has a high carrier-transport property is provided. A composite material having a good property of carrier injection into an organic compound is provided. A composite mat

High-brightness solution-processed phosphorescent OLEDs with pyrimidine-based iridium(iii) complexes

Tong, Bi-Hai,Mei, Qun-Bo,Tian, Ru-Qiang,Yang, Min,Hua, Qing-Fang,Shi, Yu-Jie,Ye, Shang-Hui

, p. 34970 - 34976 (2016/05/19)

Two heteroleptic cyclometalated iridium(iii) complexes, Ir(ppm)2(pic) and Ir(ppm)2(taz), using 4,6-diphenyl pyrimidine (Hppm) as a cyclometalating ligand, were successfully synthesized and characterized. Strong emission at 555 and 532 nm with high photoluminescence quantum yields of 83% and 86% in PMMA at 298 k were obtained for Ir(ppm)2(pic) and Ir(ppm)2(taz), respectively. Solution-processed organic light-emitting diodes (OLEDs) based on Ir(ppm)2(pic) and Ir(ppm)2(taz) showed high-brightness of 112 233 and 125 072 cd m-2, peak current efficiencies of 30.6 and 40.4 cd A-1 and maximum external quantum efficiencies of 10.4 and 17.3%, respectively, accompanied by very low efficiency roll-off values. The ancillary ligand taz tuned the emission to saturated green, and more importantly, it can significantly increase the spectral stability and device efficiency.

Light-emitting element

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, (2015/11/27)

A light-emitting element having high external quantum efficiency is provided. A light-emitting element having low drive voltage is provided. Provided is a light-emitting element which includes a light-emitting layer containing a phosphorescent compound, a first organic compound, and a second organic compound between a pair of electrodes. A combination of the first organic compound and the second organic compound forms an exciplex (excited complex). An emission spectrum of the exciplex overlaps with an absorption band located on the longest wavelength side of an absorption spectrum of the phosphorescent compound. A peak wavelength of the emission spectrum of the exciplex is longer than or equal to a peak wavelength of the absorption band located on the longest wavelength side of the absorption spectrum of the phosphorescent compound.

Composite material, light-emitting element, light-emitting device, electronic device, and lighting device

-

Page/Page column, (2014/01/17)

A composite material which includes an organic compound and an inorganic compound and has a high carrier-transport property is provided. A composite material having a good property of carrier injection into an organic compound is provided. A composite mat

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