25922-93-4

Upstream product

• 140866-59-7 1,2-diphenyl-3-(N,N-dimethylamino)-2-propen-1-one 
• 77287-34-4 formamide 
• 952-06-7 deoxybenzoin oxime 
• 19690-01-8 1,2-diphenylethanone O-acetyl oxime 
• 149-73-5 trimethyl orthoformate 
• 451-40-1 phenyl benzyl ketone 
• 214419-25-7 4,5-bis(2-iodophenyl)pyrimidine 

Downstream Products

• 114969-67-4 4,5-Diphenyl-pyrimidine-2-carbonitrile 
• 114969-71-0 5,6-Diphenyl-pyrimidine-4-carbonitrile 
• 114969-49-2 4,5-Diphenyl-pyrimidine 1-oxide 

Relevant academic research and scientific papers

Catalyst free synthesis of mono- and disubstituted pyrimidines from O-acyl oximes

Transition-metal or iodine catalyzed transformations of O-acyl oximes to various N-heterocycles are well established. Herein, we report a catalyst free, oxime carboxylate based, three-component condensation method to access mono- and disubstituted pyrimidines. A broad range of substituted pyrimidines were prepared in moderate to excellent yields. Control experiments reveal that in situ generated formamidine is the key intermediate.

The amine exchange/biaryl coupling sequence: A direct entry to the phenanthro[9,10-d]heterocyclic framework

Novel phenanthro[9,10-d]pyrimidines and phenanthro[9,10-d][1,2]oxazoles are regioselectively prepared by the application of a straightforward synthetic pathway, starting from new o,o′-dihalogenated and non-halogenated 4,5-diarylpyrimidines and 4,5-diaryli