259222-20-3Relevant academic research and scientific papers
Towards small molecule inhibitors of mono-ADP-ribosyltransferases
Ekblad, Torun,Lindgren, Anders E.G.,Andersson, C. David,Caraballo, Rémi,Thorsell, Ann-Gerd,Karlberg, Tobias,Spjut, Sara,Linusson, Anna,Schüler, Herwig,Elofsson, Mikael
supporting information, p. 546 - 551 (2015/04/14)
Protein ADP-ribosylation is a post-translational modification involved in DNA repair, protein degradation, transcription regulation, and epigenetic events. Intracellular ADP-ribosylation is catalyzed predominantly by ADP-ribosyltransferases with diphtheri
Synthesis, anticholinesterase activity and structure-activity relationships of m-Aminobenzoic acid derivatives
Trujillo-Ferrara, Jose,Montoya Cano, Leticia,Espinoza-Fonseca, Michel
, p. 1825 - 1827 (2007/10/03)
The synthesis, acetylcholinesterase inhibitory capacity and structure-activity relationships of simple-structured m-Aminobenzoic acid derivatives are reported. Compound 1b was found to be more potent than galanthamine and tacrine in inhibiting acetylcholinesterase.
