259249-31-5

Upstream product

• 540-63-6 ethane-1,2-dithiol 

Downstream Products

• 259249-32-6 (R)-7-((4R,5R)-4,5-Bis-bromomethyl-2-methyl-[1,3]dioxolan-2-yl)-8-(4-methoxy-phenyl)-1,4-dithia-8-aza-spiro[4.5]decane 
• 259249-35-9 (R)-7-(2-Ethyl-[1,3]dithiolan-2-yl)-8-(4-methoxy-phenyl)-1,4-dithia-8-aza-spiro[4.5]decane 
• 259249-34-8 1-[(R)-8-(4-Methoxy-phenyl)-1,4-dithia-8-aza-spiro[4.5]dec-7-yl]-propan-1-one 
• 259249-33-7 1-[(R)-8-(4-Methoxy-phenyl)-1,4-dithia-8-aza-spiro[4.5]dec-7-yl]-ethanone 
• 259249-36-0 1-(4-methoxyphenyl)-2-propylpiperidine 
• 259249-38-2 {(4S,5S)-5-Hydroxymethyl-2-[(R)-8-(4-methoxy-phenyl)-1,4-dithia-8-aza-spiro[4.5]dec-7-yl]-2-methyl-[1,3]dioxolan-4-yl}-methanol 

Relevant academic research and scientific papers

Stereospecific synthesis of piperidine skeleton by [4+2] cycloaddition, leading to the synthesis of piperidines of biological interests

[4+2] Cycloaddition reaction between a chiral imine possessing an auxiliary derived from tartaric acid and Danishefsky diene was studied, and the reaction promoted by boron trifluoride etherate gave 2, 3- dehydropiperidin-4-one in a stereospecific manner. The adduct thus obtained was converted into (S)-coniine derivatives without loss of the stereochemical integrity.