259269-84-6

Usage

Uses

Used in Pharmaceutical Industry:
2-AMINO-3-BROMO-5-FLUOROBENZOIC ACID is used as a key intermediate in the synthesis of various pharmaceuticals due to its unique structural features, which can be further modified to develop new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, 2-AMINO-3-BROMO-5-FLUOROBENZOIC ACID is utilized as a building block for the development of new agrochemicals, such as pesticides and herbicides, to enhance crop protection and yield.
Used in Anti-Influenza Applications:
2-AMINO-3-BROMO-5-FLUOROBENZOIC ACID has been studied for its potential use as an anti-influenza agent, indicating its ability to inhibit the replication of influenza viruses and provide therapeutic benefits in treating influenza infections.
Used in Anti-Cancer Applications:
2-AMINO-3-BROMO-5-FLUOROBENZOIC ACID has also been investigated for its anti-cancer properties, suggesting its potential to target and inhibit the growth of cancer cells, making it a promising candidate for further research and development in oncology.
Used in Dye Production:
2-AMINO-3-BROMO-5-FLUOROBENZOIC ACID is a useful intermediate in the production of fluorescent dyes and textile dyes, contributing to the development of new dyes with improved properties and applications in various industries, such as textiles, diagnostics, and imaging.

InChI:InChI=1/C7H5BrFNO2/c8-5-2-3(9)1-4(6(5)10)7(11)12/h1-2H,10H2,(H,11,12)

Upstream product

• 446-08-2 2-amino-5-fluorobenzoic acid 

Downstream Products

• 55414-45-4 (2-amino-3-bromo-5-fluorophenyl)methanol 
• 1352717-91-9 8-bromo-6-fluoro-2-methylquinazolin-4(3H)-one 
• 1352717-90-8 6-fluoro-8-bromo-2-methyl-4H-3,1-benzoxazin-4-one 
• 953039-63-9 8-bromo-2-chloro-6-fluoroquinazoline 
• 953039-62-8 8-bromo-6-fluoro-quinazolin-2-ol 
• 953039-61-7 2-amino-3-bromo-5-fluorobenzaldehyde 

Relevant academic research and scientific papers

Amide derivative and preparation method and application thereof

The invention relates to an amide derivative and a preparation method and application thereof. The compound is an amide derivative containing 3-bromo-5-chloro (bromo) phenyl units, has obvious insecticidal activity, and can be used for killing various bio

CONDENSED-RING PYRIMIDYLAMINO DERIVATIVE, PREPARATION METHOD THEREFOR, AND INTERMEDIATE, PHARMACEUTICAL COMPOSITION AND APPLICATIONS THEREOF

Disclosed are a condensed-ring pyrimidylamino derivative, a preparation method therefor, and an intermediate, a pharmaceutical composition and applications thereof. The method for preparing the condensed-ring pyrimidylamino derivative comprises: in a solvent, in the presence of a palladium-containing catalyst, allowing a compound represented by formula I-a and a compound represented by formula I-b' to have a coupling reaction, and then preparing a compound represented by formula I by means of a deprotection reaction. Also disclosed applications of the condensed-ring pyrimidylamino derivative in the preparation of drugs for preventing, relieving and/or treating tumors or diseases caused by an anaplastic lymphoma kinase. The condensed-ring pyrimidylamino derivative of the present invention has an obvious restraint effect on the anaplastic lymphoma kinase.

FUSED RING PYRIMIDINE COMPOUND, INTERMEDIATE, AND PREPARATION METHOD, COMPOSITION AND USE THEREOF

Disclosed area fused ring pyrimidine compound, and an intermediate, a preparation method, a composition and a use thereof. The fused ring pyrimidine compound is a compound as shown in formula I, a tautomer, an enantiomer, a diastereoisomer, a pharmaceutically acceptable salt, a metabolite, a metabolic precursor or a prodrug thereof, wherein the above-mentioned compound is used for the preparation of a medicine for preventing, remitting or treating one or more of immune system diseases, autoimmune diseases, cell proliferative diseases, allergic disorders and cardiovascular diseases, and the compound has a strong inhibitory effect on the Janues kinase, FGFR kinase, FLT3 kinase and Src family kinase.

QUINAZOLINE DERIVATIVES USED TO TREAT HIV

Described herein are compounds of Formula (I) and tautomers and pharmaceutical salts thereof, compositions and formulations containing such compounds, and methods of using and making such compounds.

Preparation of 6-aminoquinazolin-4(3H)-ones via direct SNAr on the quinazoline ring

The preparation of 6-aminoquinazolin-4(3H)-ones requires the use of platinum-metal group catalysis on the corresponding C-6-iodo or 6-bromo precursors. Herein, we report to our knowledge the first successful S NAr reaction directly at the unact