2594-45-8Relevant academic research and scientific papers
Synthesis method of dinaverine hydrochloride
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, (2021/07/09)
The invention provides a synthesis method of dinaverine hydrochloride. The method comprises the following steps: S1, reacting 2, 2-diphenyl-2-glycolic acid with acyl chloride, and then adding 2-ethyl butanol and alkali for reaction to obtain an intermediate 2-(2-ethyl butoxy)-2, 2-diphenylacetic acid; s2, adding alkali and N, N-dimethylaminochloroethane hydrochloride into the intermediate for a reaction, then introducing hydrogen chloride gas for a period of time, carrying out concentration, adding ethyl acetate, filtering, and obtaining denaverine hydrochloride.
Biomimetic oxidation of denaverine hydrochloride
Smolinka, Kai,G?ber, Berthold
, p. 679 - 683 (2007/10/03)
The behavior of denaverine (1) in various chemical model systems based on metalloporphyrins as catalysts was investigated to determine the possible oxidative metabolism. The resulting derivatives were compared to a biological model system and in vivo metabolism in rat and human.
