25944-64-3

Basic information

• Product Name: Phosphonic acid, (1-phenylethenyl)-, diethyl ester
• CAS NO: 25944-64-3
• Molecular Formula: C12H17O3P
• Molecular Weight: 240.239
• Mol File: 25944-64-3.mol
• Article Data: 34

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, (1-phenylethenyl)-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, (1-phenylethenyl)-, diethyl ester(25944-64-3)
• EPA Substance Registry System: Phosphonic acid, (1-phenylethenyl)-, diethyl ester(25944-64-3)

Safety Data

• Hazardous Substances Data: 25944-64-3(Hazardous Substances Data)

Upstream product

• 3220-50-6 1-phenylvinylphosphonic acid 
• 75-03-6 ethyl iodide 
• 122-51-0 orthoformic acid triethyl ester 
• 2882-19-1 ethyl 2-phenyl-2-bromoacetate 
• 1309980-37-7 diethyl 1-[(4-methylbenzenesulfonyl)oxy]ethene-alpha-phosphonate 
• 98-80-6 phenylboronic acid 
• 919-19-7 diethyl acetylphosphonate 
• 243137-79-3 1,1,2,2,3,3,4,4,4-nonafluoro-butane-1-sulfonic acid 1-(diethoxy-phosphoryl)-vinyl ester 
• 67-56-1 methanol 
• 85166-79-6 Methanesulfonic acid 1-(diethoxy-phosphoryl)-1-phenyl-ethyl ester 
• 102-96-5 (2-nitroethenyl)benzene 
• 122-52-1 triethyl phosphite 
• 762-04-9 phosphonic acid diethyl ester 
• 98-86-2 acetophenone 

Downstream Products

• 82632-34-6 2-phenyl-3H-pyrrolizine 
• 444789-01-9 (2S,5R,2'R)-3,6-diethoxy-2-[2'-(diethoxyphosphoryl)-2'-phenylethyl]-2,5-dihydro-5-isopropylpyrazine 
• 444789-04-2 (2S,5R,2'S)-3,6-diethoxy-2-[2'-(diethoxyphosphoryl)-2'-phenylethyl]-2,5-dihydro-5-isopropylpyrazine 
• 261167-71-9 (1S,3S)-(3-amino-4-hydroxy-3-methyl-1-phenylbutyl)phosphonic acid 
• 1133079-40-9 diethyl (3-phenyl-4,5-dihydro-3H-pyrazol-3-yl)phosphonate 
• 7749-92-0 diethyl 2-formyl-1-phenylethylphosphonate 
• 884489-14-9 (3-benzyloxyamino-1-phenyl-propyl)-phosphonic acid diethyl ester 
• 852326-96-6 [3-(acetyl-benzyloxy-amino)-1-phenyl-propyl]-phosphonic acid diethyl ester 

Relevant articles and documents

Highly enantioselective hydrogenation of α,β-unsaturated phosphonates with iridium-phosphinooxazoline complex: Synthesis of a phosphorus analogue of naproxen

A number of pharmaceutically interesting optically active 1-arylethylphosphonates, including a phosphorus analogue of naproxen, has been synthesized with ee 92-95% via asymmetric hydrogenation under mild conditions using [Ir(cod)(phosphine oxazoline)]sup

Asymmetric hydrogenation of diethyl 1-phenylvinylphosphonate by metal complexes in CH2Cl2 and in supercritical carbon dioxide using phosphite-type ligands

Asymmetric hydrogenation of diethyl 1-phenylvinylphosphonate was carried out for the first time in dichloromethane and supercritical carbon dioxide in the presence of phosphite and amidophosphite ligands. The catalysts based on [Ir(COD)2]BARF (COD is 1,5-

Markovnikov-addition of H-phosphonates to terminal alkynes under metal- And solvent-free conditions

An addition of H-phosphonates to aryl alkynes was realized under solvent- and metal-free conditions, affording Markovnikov-selective α-vinylphosphonates in moderate to good yields. A wide range of aryl alkynes could be applied for the reaction. A tentative mechanism of addition-substitution was proposed based onin situ31P {1H} NMR studies.

Rhenium-Catalyzed Decarboxylative Tri-/Difluoromethylation of Styrenes with Fluorinated Carboxylic Acid-Derived Hypervalent Iodine Reagents

Herein, unprecedented rhenium-catalyzed decarboxylative oxytri-/difluoromethylation and Heck-type trifluoromethylation of styrenes have been developed by using hypervalent iodine(III) reagents derived from cheap, stable, and easy-handling fluorinated carboxylic acids. Mechanistic studies revealed a radical decarboxylative trifluoromethylation pathway occurring in these reactions.