25947-04-0Relevant academic research and scientific papers
Rapid Access to New Angular Phenothiazine and Phenoxazine Dyes
Onoabedje, Efeturi A.,Okoro, Uchechukwu C.,Knight, David W.
, p. 206 - 214 (2017)
The synthesis of some new thiophenyl-derivatized and furanyl-derivatized phenothiazine and phenoxazine dyestuffs is described. This was achieved by two methods after the synthesis of 6-chloro-5H-benzo[a]phenothiazin-5-one, 6-chloro-5H-benzo[a]phenoxazin-5-one, and 6-chloro-5H-naphtho[2,1-b]pyrido[2,3-e][1,4]oxazin-5-one intermediates via anhydrous base condensation reaction of 2,3-dichloro-1,4-naphthoquinone with 2-aminothiophenol, 2-aminophenol, and 2-aminopyridinol, respectively. The first method involved treatment of tributyl(thien-2-yl) or tributyl(furan-2-yl) stannane with chlorophenothiazine/chlorophenoxazine under mild basic chemical formula (CsF) and 1,4-dioxane or toluene solvent at 80°C to supply dazzling yellow solid in high yields. In the second method, the catalytic system was pre-activated in acetonitrile, followed by addition of coupling partners and K3PO4to obtain high melting and variety of highly colored products in moderate to high yields. The reaction conditions were compatible with unprotected N–H and carbonyl functional groups. The intense colors of these dyes and their ease of re-oxidation of Na2S2O4-reduced derivatives make them suitable as vat dyes. Also, they were found to be good colorants for textiles, papers, paint, ink, soap, polish, candle, and plastic materials.
The Dehalogenation of the Halo Substituted 5H-Benzophenothiazin-5-ones and 3H-Phenothiazin-3-ones
Koshitani, Jinya,Ueno, Yoshio
, p. 233 - 236 (1982)
6-Bromo- and 6-chloro-5H-benzophenothiazin-5-ones were dehalinated to 5H-benzophenothiazin-5-one in the presence of sodium hydrosulfite (disodiumdithionite*2 H2O) dissolved in aqueous pyridine under nitrogen atmosphere.Keywords: 5H-Benzophenothiazin-5-one; 6-Bromo-5H-benzophenothiazin-5-one; 6-Chloro-5H-benzophenothiazin-5-one; 3H-Phenothiazin-3-one.
Ecofriendly syntheses of phenothiazones and related structures facilitated by laccase – a comparative study
Cannatelli, Mark D.,Ragauskas, Arthur J.
supporting information, p. 3749 - 3753 (2016/07/26)
The biocatalytic synthesis of phenothiazones and related compounds has been achieved in an aqueous system under mild conditions facilitated by laccase oxidation. It was found that by coupling 2-aminothiophenol directly with 1,4-quinones, the product yield
Heteroannulation of naphthoquinones. Studies on the reaction of 2-bromo-2,3-dihydronaphthoquinone derivatives with 1,2-binucleophiles
Couladouros, Elias A.,Plyta, Zoi F.,Iliadis, Theodoras,Roussis, Vassilios,Papageorgiou, Vassilios P.
, p. 709 - 714 (2007/10/03)
Heterocyclic derivatives of naphthoquinones were synthesized via their 2-bromo-2,3-dehydro-intermediates. This new route may lead to the formation of benzo[a]phenothiazin-5-ones, benzo[f]quinoxalin-6-ones as well as their 1,4 (or 7,10) dihydroxy-derivatives in high yields. The possible mechanisms involved in the formation of these compounds are discussed.
1H AND 13C CHEMICAL SHIFT DATA OF SOME OMMOCHROME MODELS: SUBSTITUTED BENZO-5H-PHENOXAZIN-5-ONE
Bolognese, Adele,Parilli, Michelangelo
, p. 1829 - 1833 (2007/10/02)
1H and 13C chemical shift data are reported for some substituted benzo-5H-phenoxazin-5-ones, that are convenient models of natural ommochromes.Assignments are based on one- and two-dimensional techniques.
Phenothiazone derivatives and analogs
-
, (2008/06/13)
Phenothiazone derivatives and analogs thereof, pharmaceutical compositions and methods of treatment are disclosed. These compounds are useful as inhibitors of mammalian leukotriene biosynthesis. As such, these compounds are useful therapeutic agents for treating allergic conditions, asthma, cardiovascular disorders and inflammation.
