214-97-1Relevant academic research and scientific papers
Syntheses of new pyridoxazines, benzoxa(thia)azines, and benzoxa(thia)azepines via cyclocondensation and elimination reactions between donors and acceptors
Aly, Ashraf A.,Hassan, Alaa A.,El-Shaieb, Kamal M.,Shaker, Rafaat M.
, p. 999 - 1005 (2005)
Reaction of 3-amino-2-hydroxypyridine and 2-amino(thio)phenols with various selected π-acceptors are herein reported. Different modes of cyclization via elimination and/or condensation reactions were observed during the reaction of the donors with 3,4,5,6-tetrachloro-1,2-benzoquinone (CHL-o),2,3,5,6- tetrachloro-1,4-benzoquinone (CHL-p),2,3-dicyano-l,4-naphthoquinone (DCNQ) and 2-dicyanomethyleneindane-1,3-dione (CNIND). A series of pyridoxazines, benzoxa(thia)azines, benzoxa(thia)azepines has been synthesized in good yields.
A novel one-pot ionic liquid promoted synthesis of benzo[a]phenothiazine derivatives
Yadav, Ashok K.,Gupta, Manisha
, p. 1568 - 1573 (2015/02/02)
A simple, efficient and practical method for the synthesis of substituted-5H-benzo[a]phenothiazin-5-one and substituted benzo[a][1,4]benzothiazino [3,2-c] phenothiazine by the condensation reaction of 2,3-disubstituted 1,4-napthoquinone with zinc salt of
Micelles catalyzed one pot regio- and chemoselective synthesis of benzo[a]phenazines and naphtho[2,3-d]imidazoles 'in H2O'
Tandon, Vishnu K.,Verma, Manoj K.,Maurya, Hardesh K.,Kumar, Sandeep
, p. 6331 - 6334 (2014/12/10)
An efficient, novel, and concise one pot regio- and chemoselective synthesis of benzo[a]phenazines (4) and naphtho[2,3-d]imidazoles (8) has been accomplished in excellent yields by nucleophilic substitution reaction of 2,3-dichloro-1,4-naphthoquinone (1) with o-phenylenediamine (2) and benzamidines (7) respectively 'in H2O' using base and micelles (SDS) as catalyst. Analog reaction of 2,3-dichloro-1,4-naphthoquinone (1) with 2-aminobenzenethiol (9) under identical conditions led to formation of a mixture of benzo[b]phenothiazine (10), benzo[a]phenothiazine (11), and benzo[a]-1,4-benzothiazino-3,2-phenothiazine (12) in 17%, 23%, and 57% yields, respectively.
REASERCH IN THE CHEMISTRY OF HETEROCYCLIC QUINONEIMINES. 5. EFFECT OF BENZANNELATION OF PHENOTHIAZIN-3-ONE ON ITS REACTION WITH O- AND S-NUCLEOPHILES
Vysokov, V. I.,Afanas'eva, G. B.,Chupakhin, O. N.,Ufimtseva, I. S.
, p. 367 - 370 (2007/10/02)
Benzophenothiazin-5-one reacts with alkoxides,thiols or thiolates to give 6-alkoxy- and 6-alkyl(aryl)thiobenzophenothiazin-5-ones, respectively.Benzannelation of phenothiazin-3-one in the quinoneimine fragment markedly hinders reactions with O- and S-nucleophiles with retention of the reaction center in the quinoneimine fragment of the molecule.
