259532-13-3Relevant academic research and scientific papers
The identification of a potent, water soluble inhibitor of lipoprotein-associated phospholipase A2
Boyd, Helen F.,Hammond, Beverley,Hickey, Deirdre M.B.,Ife, Robert J.,Leach, Colin A.,Lewis,Macphee, Colin H.,Milliner, Kevin J.,Pinto, Ivan L.,Smith, Stephen A.,Stansfield, Ian G.,Theobald, Colin J.,Whittaker, Caroline M.
, p. 701 - 704 (2007/10/03)
Modification of the pyrimidone 5-substituent in a series of 1-((amidolinked)-alkyl)-pyrimidones, lipophilic inhibitors of lipoprotein-associated phospholipase A2, has given inhibitors of nanomolar potency and improved physicochemical properties
