25960-25-2

Usage

Uses

Used in Recreational Drug Use:
Etizolam is used as a recreational drug for its euphoric and calming effects. It is sought after for its ability to induce relaxation and alleviate anxiety, making it a popular choice among those seeking a temporary escape from stress or other emotional states.
Used in Pharmaceutical Research:
Although not approved for medical use in the United States, etizolam's potent agonist activity at the GABA-A receptor makes it a subject of interest in pharmaceutical research. Its anxiolytic, muscle-relaxant, sedative, and amnesic effects could potentially be harnessed for the development of new treatments for anxiety disorders, insomnia, and other conditions that may benefit from these properties.
Used in Drug Regulation and Control:
Due to its high potential for abuse and addiction, etizolam is a regulated substance in many countries. It is used as a reference point for drug control policies and efforts to prevent the misuse and abuse of psychoactive substances. Monitoring and regulating the availability and distribution of etizolam can help reduce the risks associated with its use and protect public health.

InChI:InChI=1/C22H22O4/c1-3-26-22(24)21-19(16-7-5-4-6-8-16)13-17(14-20(21)23)15-9-11-18(25-2)12-10-15/h4-12,14,19,21H,3,13H2,1-2H3/t19-,21+/m0/s1

Upstream product

• 141-97-9 ethyl acetoacetate 
• 959-23-9 4'-methoxychalcone 
• 100-52-7 benzaldehyde 
• 100-06-1 1-(4-methoxyphenyl)ethanone 

Downstream Products

• 933769-91-6 6-cyclohexylamido-3-p-methoxy-5-phenylcyclohex-2-enone 
• 933769-97-2 4-(4-Methoxy-phenyl)-2-oxo-6-phenyl-cyclohex-3-enecarboxylic acid (2-chloro-acetyl)-cyclohexyl-amide 
• 1190880-54-6 C₂₂H₂₁NO₃ 
• 1290639-99-4 9-(4-methoxyphenyl)-7-phenyl-1,4-diazaspiro[4.5]deca-9-ene-6-ethyl carboxylate 

Relevant academic research and scientific papers

Design, synthesis and molecular docking of novel diarylcyclohexenone and diarylindazole derivatives as tubulin polymerization inhibitors

New target compounds were designed as inhibitors of tubulin polymerization relying on using two types of ring B models (cyclohexenone and indazole) to replace the central ring in colchicine. Different functional groups (R1) were attached to man

Activated fly ash catalyzed facile synthesis of novel spiro imidazolidine derivatives as potential antibacterial and antifungal agents

An array of novel spiro imidazolidine derivatives was synthesized in dry media and was screened for their anti-microbial activities. Structure-activity relationship results revealed that compounds 22, 23 against P.aeruginosa, 24 against S.aureus, 24, 25 against K.pneumonia, 27 against S.aureus, β-H.streptococcus, 29 against M.luteus, K.pneumonia, 29, 30 against P.vulgaris exhibited excellent antibacterial activity at a minimum inhibitory concentration (MIC) value of 6.25 μg/mL. Compound 23 against M.gypseum, 25, 29 against Candida 6 and 29, 30 against C.albicans revealed excellent antifungal activity at a MIC value of 6.25 μg/mL.

Synthesis, spectral analysis, and in vitro microbiological evaluation of ethyl 7,9-diaryl-1, 4-diazaspiro[4.5]dec-9-ene-6-carboxylates as a new class of antibacterial and antifungal agents

A series of novel ethyl 7,9-diaryl-1,4-diazaspiro[4.5]dec-9-ene-6- carboxylates was synthesized by the reaction of ethyl 4,6-diaryl-2-oxocyclohex- 3-ene-1-carboxylates with ethylenediamine in the presence of p-toluenesulfonic acid without a solvent under focused microwave irradiation. The title compounds were screened for their antimicrobial activities against a spectrum of clinically isolated microorganisms.

Microwave assisted rapid and efficient. synthesis of new 3-ethoxy-4,6-diaryl-4,5- Dihydro-2,1-benzisoxazoles

A simple, extremely fast and efficient synthesis of new 3- ethoxy-4,6-diaryl-4,5-dihydro2,l-benzisoxazoles has been achieved under microwave irradiation.