25988-61-8

Basic information

• Product Name: acetyl L-cysteinate
• CAS NO: 25988-61-8
• Molecular Formula: C₅H₉NO₃S
• Molecular Weight: 163.1949
• Mol File: 25988-61-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 222.6°C at 760 mmHg
• Flash Point: 88.4°C
• Density: 1.257g/cm³
• Vapor Pressure: 0.101mmHg at 25°C
• Refractive Index: 1.503
• CAS DataBase Reference: acetyl L-cysteinate(CAS DataBase Reference)
• NIST Chemistry Reference: acetyl L-cysteinate(25988-61-8)
• EPA Substance Registry System: acetyl L-cysteinate(25988-61-8)

Safety Data

• Hazardous Substances Data: 25988-61-8(Hazardous Substances Data)

Upstream product

• 52-90-4 L-Cysteine 
• 75-36-5 acetyl chloride 
• 546-88-3 acetylhydroxamic acid 
• 830-03-5 4-nitrophenol acetate 

Relevant articles and documents

Direct Observation of Acyl Nitroso Compounds in Aqueous Solution and the Kinetics of Their Reactions with Amines, Thiols, and Hydroxamic Acids

Acyl nitroso compounds or nitrosocarhonyls (RC(O)N=O) are reactive short-lived electrophiles, and their hydrolysis and reactions with nucleophiles produce HNO. Previously, direct detection of acyl nitroso species in nonaqueous media has been provided by time-resolved infrared spectroscopy demonstrating that its half-life is about 1 ms. In the present study hydroxamic acids (RC(O)NHOH) are oxidized electrochemically in buffered aqueous solutions (pH 5.9-10.2) yielding transient species characterized by their maximal absorption at 314-330 nm. These transient species decompose via a first-order reaction yielding mainly HNO and the respective carboxylic acid and therefore are ascribed to RC(O)N=O. The sufficiently long half-life of RC(O)N=O in aqueous solution allows for the first time the study of the kinetics of its reactions with various nucleophiles demonstrating that the nucleophilic reactivity follows the order thiolate > hydroxamate > amine. Metal chelates of CH3C(O)NHOH catalyze the hydrolysis of CH3C(O)N=O at the efficacy order of CuII > ZnII > NiII > CoII where only CuII catalyzes the hydrolysis also in the absence of the hydroxamate. Finally, oxidation of hydroxamic acids generates HNO, and the rate of this process is determined by the half-life of the respective acyl nitroso compound.

Transition state stabilization by micelles: Thiolysis of p-nitrophenyl alkanoates in cetyltrimethylammonium bromide micelles

Thiolysis of p-nitrophenyl esters (acetate to decanoate) by the anion of 2-mercaptoethanol (ME) is catalyzed by micelles of cetyltrimethylammonium bromide (CTAB) in aqueous solution. At fixed [ME], the observed rate constants (k(obs)) show saturation with